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    Recombinant Anti-human CASP7 Intrabody [Tat] (CAT#: IAB-B072(T))

    Recombinant anti-CASP7 intrabody in fusion with HIV Tat works within cells to bind human CASP7, expressed in CHO cells.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Small intestine
    Figure 1 Small intestine
    (Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_4_2.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_7_3.jpg
    Figure 3 Kidney
    Figure 3 Kidney
    (Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_9_5.jpg
    Figure 4 Testis
    Figure 4 Testis
    (Spermatogonia cells Staining: Medium Intensity: Moderate)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_4_6.jpg
    Figure 5 Lymph node
    Figure 5 Lymph node
    (Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/25563/59600_A_9_8.jpg
    RNA Expression
    Figure 6 RNA cell line category: Low cell line specificity
    Figure 6 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000165806-CASP7

    Specifications

    • Immunogen
    • human caspase 7, apoptosis-related cysteine peptidase
    • Host Species
    • human
    • Type
    • scFv-Tat
    • Cell Penetrating Peptide
    • TAT
      TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
    • Species Reactivity
    • human
    • Applications
    • Formats of immunological tests: Immunofluorescence; Flow Cytometry; Functional studies

    Product Property

    • Purity
    • >95% (SDS-PAGE)
    • Storage
    • Store at -20°C. Avoid multiple freeze/thaw cycles.

    Target

    • Alternative Names
    • Apoptosis related cysteine peptidase; Apoptosis related cysteine protease; Apoptotic protease MCH 3; Apoptotic protease Mch-3; Apoptotic protease MCH3; CASP 7; CASP-7; CASP7; CASP7_HUMAN; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CASP7"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Intrabody Products Rabbit Monoclonal Antibody Products IgG Antibody Products Antibody Magnetic Beads IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    IAB-B072(A) Recombinant Anti-human CASP7 Intrabody [(D-Arg)9] WB, ICC, FuncS scFv-(D-Arg)9
    IAB-B072(G) Recombinant Anti-human CASP7 Intrabody [+36 GFP] WB, ICC, Neut, FuncS scFv-(+36GFP)

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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