Mouse Anti-CASP8 Recombinant Antibody (clone 24C10)
CAT#: MOB-1464z
This product is a mouse antibody that recognizes human CASP8. It can be used in the following applications: WB, ELISA, FCM, IHC.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1302/69_H9_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6191/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows strong positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2047/5614_A_8_2_selected.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1302/30722_A_6_6.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1302/30722_A_9_8.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1302/30722_A_7_5.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000064012-CASP8
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Specifications
- Immunogen
- Human Caspase 8, Apoptosis-Related Cysteine Peptidase
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human CASP8
- Species Reactivity
- Human
- Clone
- 24C10
- Applications
- WB, ELISA, FC, IHC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western blot, Enzyme-linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry.
Target
- Alternative Names
- CASP8; MCH5; MORT1-Associated Ced-3 Homolog; Casp-8; FADD-Like ICE; Apoptotic Protease Mch-5; MACH; Caspase 8, Apoptosis-Related Cysteine Peptidase; FADD-Homologous ICE/CED-3-Like Protease; ALPS2B; MACH-Alpha-1/2/3 Protein; FLICE; MACH-Beta-1/2/3/4 Protei
- UniProt ID
- Q14790
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "CASP8"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0330CT | Mouse Anti-CASP8 Recombinant Antibody (clone 1H11) | WB | Mouse IgG1 |
| ZG-0072J | Mouse Anti-CASP8 Recombinant Antibody (clone 2G12) | WB, IF, ICC, IHC-P | Mouse IgG |
| VS4-WK63 | Mouse Anti-CASP8 Recombinant Antibody (VS4-WK63) | ELISA, WB, IHC | Mouse IgG |
| VS3-FY1673 | Rabbit Anti-CASP8 Recombinant Antibody (clone R02-0D7) | WB | Rabbit IgG |
| VS13-YC132 | Rabbit Anti-CASP8 Recombinant Antibody (VS13-YC132) | WB, ICC, IF, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0082MZ | Chicken Anti-Caspase 8 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0479 | Hi-Affi™ Rabbit Anti-CASP8 Recombinant Antibody (clone DS479AB) | FC, IHC-P, IP, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY321 | Anti-CASP8 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1009 | Anti-Mouse CASP8 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1012 | Anti-Human CASP8 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1010 | Anti-Monkey CASP8 Immunohistochemistry Kit | IHC |
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