Afuco™ Anti-Human CCR5 ADCC Recombinant Antibody (HGS004), ADCC Enhanced
CAT#: AFC-097CL
Anti-CCR5 ADCC Enhanced Antibody (HGS004) is an ADCC enhanced antibody produced by our Afuco™ platform. HGS004 is a human immunoglobulin (Ig) G4 monoclonal antibody against CCR5. HGS004 binds to and inhibits the activity of the CCR5 receptor on the cell surface. HIV uses both the CCR5 and the CD4 receptors to gain entry to the cell, but CCR5 is the primary receptor enabling HIV transmission and replication from the early stages of infection through to progression to AIDS.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160791-CCR5
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- HIV Infection
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- ≤1 year at -20°C.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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