Afuco™ Anti-Human CCR5 ADCC Recombinant Antibody (HGS004), ADCC Enhanced (CAT#: AFC-097CL)
Anti-CCR5 ADCC Enhanced Antibody (HGS004) is an ADCC enhanced antibody produced by our Afuco™ platform. HGS004 is a human immunoglobulin (Ig) G4 monoclonal antibody against CCR5. HGS004 binds to and inhibits the activity of the CCR5 receptor on the cell surface. HIV uses both the CCR5 and the CD4 receptors to gain entry to the cell, but CCR5 is the primary receptor enabling HIV transmission and replication from the early stages of infection through to progression to AIDS.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160791-CCR5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160791-CCR5
Figure 1 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160791-CCR5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160791-CCR5
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- HIV Infection
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- CCR5; chemokine (C-C motif) receptor 5 (gene/pseudogene); CKR5; CCR-5; CD195; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5; C-C chemokine receptor type 5; chemr13; HIV-1 fusion coreceptor; chemokine receptor CCR5; C-C motif chemokine receptor 5 A159A
- Gene ID
- 1234
- UniProt ID
- P51681
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-078 | Recombinant Anti-mouse Ccr5 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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