A monoclonal antibody that binds to the CD151 protein. This product is capable of inhibiting the development of primary tumors and of inhibiting its metastasispromoting activity.
Figure 1 Characterization of CD151 mAb 9B.
Western blot analysis for CD151 in HCCLM3 cells and recombinant CD151 protein using CD151 mAb 9B.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 2 Characterization of CD151 mAb 9B.
Co-IP assay using anti-human CD151 mAb 9B in HCCLM3 cells.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 3 Characterization of CD151 mAb 9B.
CD151 mAb 9B inhibits Akt signaling in HCCLM3 cells.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 4 Localization and Expression of CD151 Protein in HCCs.
Immunofluorescent staining with CD151 mAb 9B in HCCLM3 cells.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 5 Localization and Expression of CD151 Protein in HCCs.
Immunohistochemical staining with CD151 mAb 9B in HCC tissues.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 6 Localization and Expression of CD151 Protein in HCCs.
FACS analysis of CD151 mAb 9B binding to the QRD194-196 conformational epitope of CD151 in HCC cells.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 7 The effect of CD151 mAb 9B on HCCs.
Wound healing assay for the effect of CD151 mAb 9B on the mobility of tumor cells.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
Figure 8 CD151 mAb 9B Inhibited the progression of HCCs in vivo.
IHC staining for CD34 and CD151 to assay the effect of CD151 mAb 9B on neoangiogenesis.
Ke, A. W., Zhang, P. F., Shen, Y. H., Gao, P. T., Dong, Z. R., Zhang, C., ... & Kang, Q. (2016). Generation and characterization of a tetraspanin CD151/integrin α6β1-binding domain competitively binding monoclonal antibody for inhibition of tumor progression in HCC. Oncotarget, 7(5), 6314.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1623z | Mouse Anti-CD151 Recombinant Antibody (clone 24G4) | WB, FC, ICC, IHC, FuncS | Mouse IgG1 |
HPAB-0212-CN | Mouse Anti-CD151 Recombinant Antibody (clone TS151r) | FC, IP, IHC, IF, Inhib, WB | Mouse IgG |
HPAB-0213-CN | Mouse Anti-CD151 Recombinant Antibody (clone TS151) | IF, FuncS, IB, WB, FC, IHC, IP | Mouse IgG |
FAMAB-1034CQ | Human Anti-CD151 Recombinant Antibody (clone 11G5a) | IP, FC, FuncS, IHC | Human IgG1 |
VS3-XY208 | Mouse Anti-CD151 Recombinant Antibody (clone 3G1) | WB, IP, IF, IHC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1601CL | Anti-Human CD151 Recombinant Antibody (203B6) | FC, FuncS | |
TAB-1602CL | Anti-Human CD151 Recombinant Antibody (205H8) | FC, FuncS | |
TAB-1603CL | Anti-Human CD151 Recombinant Antibody (211F3) | FC, FuncS | |
TAB-1604CL | Anti-Human CD151 Recombinant Antibody (214B2) | FC, FuncS | |
TAB-1601CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (203B6) | FC, FuncS |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1605CL | Anti-Human CD151 Recombinant Antibody (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
TAB-1605CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
TAB-1606CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (c214B2) | ELISA, FC, WB, Block, FuncS | Chimeric antibody (mouse/human) |
TAB-1605CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (c203B6) | ELISA, FC, WB | Chimeric antibody (mouse/human) |
TAB-1606CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (c214B2) | ELISA, FC, WB, Block, FuncS | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1607CL | Anti-Human CD151 Recombinant Antibody (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
TAB-1608CL | Anti-Human CD151 Recombinant Antibody (Humanized 214B2) | FC, FuncS, WB | Humanized antibody |
TAB-1607CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
TAB-1608CL-S(P) | Anti-Human CD151 Recombinant Antibody scFv Fragment (Humanized 214B2) | FC, FuncS, WB | Humanized antibody |
TAB-1607CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (Humanized 203B6) | FC, FuncS, WB | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-285CQ | Mouse Anti-CD151 Recombinant Antibody (clone 50-6) | FC, ICC, WB, Block | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0533 | Hi-Affi™ Rabbit Anti-CD151 Recombinant Antibody (clone DS533AB) | WB, IHC, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0212-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone TS151r); scFv Fragment | WB, FC, IHC, IP | Mouse scFv |
HPAB-0213-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone TS151); scFv Fragment | WB, FC, IHC, IP | Mouse scFv |
HPAB-0214-CN-S(P) | Mouse Anti-CD151 Recombinant Antibody (clone 9B); scFv Fragment | WB, ELISA, IHC, IF, Co-IP | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0212-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone TS151r); Fab Fragment | WB, FC, IHC, IP | Mouse Fab |
HPAB-0213-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone TS151); Fab Fragment | WB, FC, IHC, IP | Mouse Fab |
HPAB-0214-CN-F(E) | Mouse Anti-CD151 Recombinant Antibody (clone 9B); Fab Fragment | WB, ELISA, IHC, IF, Co-IP | Mouse Fab |
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