Anti-Human CD151 Recombinant Antibody (203B6) (CAT#: TAB-1601CL)
This antibody is capable of binding specifically to the human CD151 protein, which can be used as a medicament for the prophylactic and/or therapeutic treatment of cancers and in diagnostic methods or kits for diseases associated with overexpression of the CD151 protein.
Specific Inquiry
FC
Figure 1 The flow cytometry analysis of the recognition of CD151 by the antibody 203B6 on the surface of NIH 3T3-CD151, PC3 and A549 cells.
FuncS
Figure 2 The anti-tumor activity of anti-CD151 monoclonal antibodies in the PC3 prostate tumor xenograft model.
Swiss mice Nude (n = 6) were grafted subcutaneously with PC3 cells. Five days after the cell transplant, the mice receive, ip, a dose of 2 mg / mouse of the test antibody followed by two administrations per week of a dose of 1 mg / mouse of this antibody. The tumor volume is evaluated by the formula [pi] / 6 x length x width x thickness.
Figure 3 The study of the binding of the radiolabeled antibody 203B6 on PC3 cells: Determination of the equilibrium affinity constant with (A) saturation curve and (B) Scatchard plot.
FuncS
Figure 4 The effect of anti-CD151 antibodies on platelet functions with (A) Platelet Aggregation and (B) Platelet Activation (Serotonin Release).
FuncS
Figure 5 The effect of anti-CD151 antibodies on in vivo tumor growth of NCI-H441 cells.
Specifications
- Immunogen
- NIH 3T3 cells expressing human CD151
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 203B6
- Applications
- FC, FuncS
- Related Disease
- Cancers
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry and Functional Assay.
Target
- Alternative Names
- CD151; CD151 molecule (Raph blood group); GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24; CD151 antigen; tspan-24; tetraspanin-24; membrane glycoprotein SFA-1; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; platelet surface glycoprotein gp27; platelet-endothelial tetraspan antigen 3; platelet-endothelial cell tetraspan antigen 3
- Gene ID
- 977
- UniProt ID
- A0A024RCB3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1602CL | Anti-Human CD151 Recombinant Antibody (205H8) | FC, FuncS | |
| TAB-1603CL | Anti-Human CD151 Recombinant Antibody (211F3) | FC, FuncS | |
| TAB-1604CL | Anti-Human CD151 Recombinant Antibody (214B2) | FC, FuncS | |
| TAB-1601CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (203B6) | FC, FuncS | |
| TAB-1602CL-F(E) | Anti-Human CD151 Recombinant Antibody Fab Fragment (205H8) | FC, FuncS |
Customer Reviews and Q&As
Customer Review
Q&As
Great for Cell Migration Studies
We used this antibody to track CD151 involvement in cell migration. The staining was excellent and helped us uncover some crucial insights.
Consistent Results
I've used this antibody in multiple experiments with consistent and reproducible results. It's become a staple in my lab.
Useful in Cancer Research
Critical tool for cancer research. Helped us delineate the role of CD151 in tumor metastasis with precise targeting and strong signals.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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