Anti-Human CD151 Recombinant Antibody (Humanized 214B2) (CAT#: TAB-1608CL)
This antibody is capable of binding specifically to the human CD151 protein, which can be used as a medicament for the prophylactic and/or therapeutic treatment of cancers and in diagnostic methods or kits for diseases associated with overexpression of the CD151 protein.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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FC
Figure 1 shows the analysis, by flow cytometry, of the recognition of CD151 by the murine antibody 214B2 on the surface of NIH 3T3-CD151 cells.
FC
Figure 2 shows the results of evaluation of the specificity of antibodies 20386, 205H8, 211F3 and 21482 by Western blot.
WB
Figure 3 illustrates the anti-tumour activity of anti-CD151 monoclonal antibodies in the PC3 prostate tumour xenograft model.
The PC3 cells were grafted into Swiss Nude mice (n=6) by the subcutaneous route. Five days after grafting of the cells, the mice receive, by the i.p. route, a challenge dose of 2 mg/mouse of the antibody under test followed by two administrations per week of a dose of 1 mg/mouse of that antibody. The tumour volume is determined by the formula π/6×length×width×thickness.
FuncS
Figure 4 shows the effect of the anti-CD151 antibodies on platelet functions with Platelet aggregation.
FuncS
Figure 5 shows the effect of anti-CD151 antibodies on the tumour growth, in vivo, of NCI-H441 cells.
FuncS
![Figure 6 illustrates the in vivo activity of the c214B2[IgG1] Mab on tumor growth of PC3, an androgen-independent prostate cell line.](https://img.creativebiolabs.net/productimages/TAB-1608CL-6.png)
Figure 6 illustrates the in vivo activity of the c214B2[IgG1] Mab on tumor growth of PC3, an androgen-independent prostate cell line.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- Humanized 214B2
- Applications
- FC, FuncS, WB
- Related Disease
- Cancers
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytotoxicityometry, Functional Assay, Western Blot.
Target
- Alternative Names
- CD151; CD151 molecule (Raph blood group); GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24; CD151 antigen; tspan-24; tetraspanin-24; membrane glycoprotein SFA-1; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; platelet surface glycoprotein gp27; platelet-endothelial tetraspan antigen 3; platelet-endothelial cell tetraspan antigen 3
- Gene ID
- 977
- UniProt ID
- A0A024RCB3
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1623z | Mouse Anti-CD151 Recombinant Antibody (clone 24G4) | WB, FC, ICC, IHC, FuncS | Mouse IgG1 |
| MOB-0383CT | Mouse Anti-CD151 Recombinant Antibody (clone 22H6b) | ELISA, FC, IF, IHC-Fr, IHC-P, IP, WB | Mouse IgG1 |
| HPAB-0212-CN | Mouse Anti-CD151 Recombinant Antibody (HPAB-0212-CN) | FC, IP, IHC, IF, Inhib, WB | Mouse IgG |
| HPAB-0213-CN | Mouse Anti-CD151 Recombinant Antibody (HPAB-0213-CN) | IF, FuncS, IB, WB, FC, IHC, IP | Mouse IgG |
| HPAB-0214-CN | Mouse Anti-CD151 Recombinant Antibody (clone 9B) | WB, Co-IP, IF, IHC, Inhib, FuncS, FC, ELISA | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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