Human Anti-CD2 Recombinant Antibody (clone 35.1) (CAT#: HPAB-0019-LSX)

Recombinant monoclonal antibody to CD2. Clone 35.1 is a chimeric antibody that can be potentially used in preventing the production of the human immunodeficiency virus (HIV-1) in HIV-1-infected T cells.


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  • Gene Expression
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Figure 1 A graph showing, by fluorescence-activated cell sorting, that chimeric monoclonal antibody CD2 SFv-Ig competes effectively with murine anti-CD2 monoclonal antibody 35.1 for binding to CD2 antigen on Jurkat T cells.

Figure 1 A graph showing, by fluorescence-activated cell sorting, that chimeric monoclonal antibody CD2 SFv-Ig competes effectively with murine anti-CD2 monoclonal antibody 35.1 for binding to CD2 antigen on Jurkat T cells.

FuncS

Figure 2 A dose-response curve for treatment of infected cells with chimeric humanized monoclonal antibody CD2 SFv-Ig, murine anti-CD2 monoclonal antibody, and CD5-Ig fusion protein antibody as a control, plotted against the inhibition of production of HIV-1 p24 antigen.

Figure 2 A dose-response curve for treatment of infected cells with chimeric humanized monoclonal antibody CD2 SFv-Ig, murine anti-CD2 monoclonal antibody, and CD5-Ig fusion protein antibody as a control, plotted against the inhibition of production of HIV-1 p24 antigen.


Specifications

  • Host Species
  • Human
  • Derivation
  • Chimeric
  • Type
  • Chimeric IgG
  • Specificity
  • Human CD2
  • Species Reactivity
  • Human
  • Clone
  • 35.1
  • Applications
  • ELISA, FuncS
  • Related Disease
  • AIDS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been tested for use in Functional Assay.

Target

  • Alternative Names
  • CD2 Molecule; CD2 Antigen (P50), Sheep Red Blood Cell Receptor; T-Cell Surface Antigen T11/Leu-5; Erythrocyte Receptor; Rosette Receptor; LFA-3 Receptor; LFA-2; SRBC; Lymphocyte-Function Antigen-2; CD2 Antigen; T11

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 35.1"

See other products for "CD2"

Intrabody

CAT Product Name Application Type
IAB-B074(A) Recombinant Anti-human CD2 Intrabody [(D-Arg)9] PCA, WB, FuncS scFv-(D-Arg)9
IAB-B074(G) Recombinant Anti-human CD2 Intrabody [+36 GFP] ELISA, IF, Neut, FuncS scFv-(+36GFP)
IAB-B074(T) Recombinant Anti-human CD2 Intrabody [Tat] ELISA, Neut, FuncS scFv-Tat

Humanized Antibody

CAT Product Name Application Type
TAB-104 Anti-Human CD2 Recombinant Antibody (Siplizumab) ELISA, IP, FC, FuncS, Neut, IF, ICC IgG1 - kappa

Rat Antibody

CAT Product Name Application Type
TAB-110CL Anti-Human CD2 Recombinant Antibody (BTI-322) FuncS Antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-295CQ Mouse Anti-CD2 Recombinant Antibody (clone CBL975) WB, FC, Neut, IHC Mouse IgG1, κ
NEUT-296CQ Mouse Anti-CD2 Recombinant Antibody (clone RPA-2.10) WB, Neut, FC, IHC, IHC-Fr Mouse IgG1, κ
NEUT-297CQ Mouse Anti-CD2 Recombinant Antibody (clone TS1/8) Neut, FC, CyTOF Mouse IgG1
NEUT-299CQ Rat Anti-CD2 Recombinant Antibody (clone 12-15) Neut, FC, IP Rat IgG1, κ
NEUT-300CQ Rat Anti-CD2 Recombinant Antibody (clone RM2) FC, FuncS, Neut Rat IgG2b, λ

Blocking Antibody

CAT Product Name Application Type
NEUT-298CQ Mouse Anti-CD2 Recombinant Antibody (clone TS218) Block, FC, IP, WB Mouse IgG1, κ
NEUT-301CQ Rat Anti-CD2 Recombinant Antibody (clone RM2-5) FC, IP, Block, Costim Rat IgG2b, λ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0542 Hi-Affi™ Rabbit Anti-CD2 Recombinant Antibody (clone DS542AB) WB, IHC, ICC, IP Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0019-LSX-S(P) Human Anti-CD2 Recombinant Antibody (clone 35.1); scFv Fragment ELISA Mouse scFv

Fab Fragment Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-104 Afuco™ Anti-CD2 ADCC Recombinant Antibody (Siplizumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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