Mouse Anti-CD209 Recombinant Antibody (clone 1G4); scFv Fragment (CAT#: HPAB-0242-YC-S(P))
Antibodies to DC-SIGN are disclosed which are capable of modulating the interaction of dendritic cells and T cells. The antibodies inhibit the interaction of dendritic cells and T cells. The antibodies also are combined with peptides which are internalized in dendritic cells and presented to T cells, thereby generating an immune response to the peptide.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/33831/67269_B_6_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/33831/67269_B_6_4.jpg
Figure 2 NA cell line categoryi: Cell line enriched (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090659-CD209
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090659-CD209
Figure 2 NA cell line categoryi: Cell line enriched (THP-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090659-CD209
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000090659-CD209
Specifications
- Immunogen
- Immature dendritic cells
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human CD209
- Species Reactivity
- Human
- Clone
- 1G4
- Applications
- FC
- Related Disease
- Viral infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD209 Molecule; Dendritic Cell-Specific ICAM-3-Grabbing Non-Integrin 1; C-Type Lectin Domain Family 4 Member L; CD209 Antigen; DC-SIGN1; DC-SIGN; CLEC4L; Dendritic Cell-Specific Intracellular Adhesion Molecules (ICAM)-3 Grabbing Non-Integrin; Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Non-Integrin; C-Type Lectin Domain Family 4, Member L; HIV Gpl20-Binding Protein; CDSIGN
- Gene ID
- 30835
- UniProt ID
- Q9NNX6
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1274z | Mouse Anti-CD209 Recombinant Antibody (clone 40G9) | FC, FuncS | Mouse IgG1 |
| MOB-1343MZ | Mouse Anti-CD209 Recombinant Antibody (clone 230608) | FC | Mouse IgG2b |
| HPAB-0242-YC | Mouse Anti-CD209 Recombinant Antibody (clone 1G4) | FC | Mouse IgG |
| HPAB-1664-FY | Mouse Anti-CD209 Recombinant Antibody (clone 1H2) | ELISA, FC | Mouse IgG1 |
| HPAB-1665-FY | Mouse Anti-CD209 Recombinant Antibody (clone 2B8) | ELISA, FC | Mouse IgG1 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-306CQ | Mouse Anti-CD209 Recombinant Antibody (clone CBL015) | Neut, WB | Mouse IgG2 |
| NEUT-309CQ | Mouse Anti-CD209 Recombinant Antibody (clone MM0239-4G10) | WB, IHC-Fr, Neut | Mouse IgG2 |
| NEUT-310CQ | Mouse Anti-CD209 Recombinant Antibody (clone DCN47.5) | FC, Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-307CQ | Mouse Anti-CD209 Recombinant Antibody (clone CBL281) | ELISA, WB, IHC, Block, FC | Mouse IgG2b |
| NEUT-308CQ | Mouse Anti-CD209 Recombinant Antibody (clone 120507) | FC, Inhib | Mouse IgG2b |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0543 | Hi-Affi™ Rabbit Anti-CD209 Recombinant Antibody (clone DS543AB) | WB, IHC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0242-YC-F(E) | Mouse Anti-CD209 Recombinant Antibody (clone 1G4); Fab Fragment | FC | Mouse Fab |
| HPAB-1664-FY-S(P) | Mouse Anti-CD209 Recombinant Antibody (clone 1H2); Fab Fragment | ELISA, FC | Mouse Fab |
| HPAB-1665-FY-S(P) | Mouse Anti-CD209 Recombinant Antibody (clone 2B8); Fab Fragment | ELISA, FC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1664-FY-F(E) | Mouse Anti-CD209 Recombinant Antibody (clone 1H2); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-1665-FY-F(E) | Mouse Anti-CD209 Recombinant Antibody (clone 2B8); scFv Fragment | ELISA, FC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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