Anti-Human CD22 Recombinant Antibody (16F7) (CAT#: TAB-1717CL)

This monoclonal antibody that specifically binds to CD22 with high affinity can be used for detecting CD22, as well as for treating various cancers and inflammatory and autoimmune disorders.

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Cyt

Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.

Figure 1 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Daudi cells.

Cyt

Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.

Figure 2 is a graph shows ADCC activity (as measured by % lysis) of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 against Raji cells.

FuncS

Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.

Figure 3 is a bar graph shows the internalization of anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 into Raji cells.

FuncS

Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.

Figure 4 is a bar graph shows the effect of immobilized anti-CD22 human antibodies 12C5, 19A3, 16F7 and 23C6 on BCR-stimulated Ramos cells, as measured by % cell death.


Specifications

  • Immunogen
  • The extracellular domain of human CD22 and the full-length CD22 protein expressed on CHO cells
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Fully human antibody
  • Specificity
  • Human
  • Clone
  • 16F7
  • Applications
  • Cyt, FuncS
  • Related Disease
  • Cancers and inflammatory and autoimmune disorders

Applications

  • Application Notes
  • This antibody has been reported for use in Cytotoxicity, Functional Assay.

Target

  • Alternative Names
  • CD22; CD22 molecule; SIGLEC2; SIGLEC-2; B-cell receptor CD22; BL-CAM; CD22 antigen; T-cell surface antigen Leu-14; B-lymphocyte cell adhesion molecule; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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