Recombinant Mouse Anti-CD28 Antibody (5.11A1) (CAT#: PABX-031)
Anti-CD28 antibody is a Mouse antibody of IgG class that binds to an CD28.
Specific Inquiry
FuncS
Figure 2 Activation markers, proliferation and cytokine release from human T cells in response to dry-coated anti-CD28 dAb-002.
Human T cells were added to wells coated with varying concentrations of Vκ dummy dAb, dAb-002, or the superagonist Ab mAb 5.11A1 and cell activation determined by increased expression of the activation Ags CD69 (A) cytokine release. The concentration of dAb or mAb 5.11A1 added to each well for dry-coating is indicated in (A). Data are mean ± SD of 10 different blood donors.
Suchard, S. J., Davis, P. M., Kansal, S., Stetsko, D. K., Brosius, R., Tamura, J., ... & Yang, Z. (2013). A monovalent anti-human CD28 domain antibody antagonist: preclinical efficacy and safety. The Journal of Immunology, 191(9), 4599-4610.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native Human CD28
- Species Reactivity
- Human
- Clone
- 5. 11A1
- Applications
- WB, ELISA, FuncS, Activ
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- The CD28 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Functional Assay, Activation.
Target
- Alternative Names
- CD28; CD28 molecule; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen;
- Gene ID
- 940
- UniProt ID
- B4E0L1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H46 | Humanized Anti-CD28 Recombinant Antibody (clone Lulizumab) | IP, IF, FuncS, FC, Neut, ELISA, IHC | Humanized V-kappa |
| TAB-064LC-S(P) | Anti-Human CD28 Recombinant Antibody scFv Fragment (TGN1412) | FC | Humanized antibody |
| TAB-065LC-S(P) | Human Anti-CD28 Recombinant Antibody; scFv Fragment (TAB-065LC-S(P)) | ELISA | Human scFv |
| TAB-066LC-S(P) | Human Anti-CD28 Recombinant Antibody; scFv Fragment (TAB-066LC-S(P)) | ELISA | Human scFv |
| TAB-069LC-S(P) | Anti-Human CD28 Recombinant Antibody scFv Fragment (HuTN228) | FC, ELISA | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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