Human Anti-CD28 Recombinant Antibody (TAB-065LC) (CAT#: TAB-065LC)
TAB-065LC is a type of humanized antibodies that target the human lymphocyte receptor CD28. When these antibodies are used in a monovalent form, they act as antagonists by blocking the CD28/B7 interaction without activating CD28. These antibodies can be used as therapeutic agents to block T cell activation through the CD28 receptor. In a dose-dependent manner, the monovalent antibody TAB-065LC reduces IL-2 synthesis by T cells.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70003/161787_A_9_8.jpg

(Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70003/161787_A_6_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000178562-CD28

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000178562-CD28
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Human IgG, κ
- Specificity
- Human CD28
- Species Reactivity
- Human
- Applications
- ELISA
- Related Disease
- Autoimmune diseases, Transplant rejection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD28"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-365 | Mouse Anti-CD28 Recombinant Antibody (clone 1C6) | WB, ELISA, FuncS | Mouse IgG1 |
MOB-0354MZ | Mouse Anti-CD28 Recombinant Antibody (clone DD29.1) | ELISA | Mouse IgG1 |
HPAB-0132CQ | Human Anti-CD28 Recombinant Antibody (clone FR255734) | ELISA, IHC, Block, FuncS | Human IgG2M3, κ |
HPAB-0245-FY | Mouse Anti-CD28 Recombinant Antibody (HPAB-0245-FY) | WB, IP, IF, FC | Mouse IgG1 |
FN-227CQ | Mouse Anti-CD28 Recombinant Antibody (clone JJ319) | FC, FuncS | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
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