This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-CD70 IgG to IFNγ. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the CD70 as well as the biological activity of IFNγ. The immunocytokine displays high levels of species-specific IFN-γ activity and selective binding to CD70 on human RCC cells. This immunocytokine was designed for treating Metastatic renal cell carcinoma.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H76 | Anti-Human CD70 Recombinant Antibody (Vorsetuzumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
TAB-882 | Anti-Human CD70 Recombinant Antibody (Vorsetuzumab Mafodotin) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
TAB-342LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-342LC-F(E)) | FC | Humanized Fab |
TAB-343LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-343LC-F(E)) | FC | Humanized Fab |
TAB-344LC-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (TAB-344LC-F(E)) | FC | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-336LC-F(E) | Anti-Human CD70 Recombinant Antibody Fab Fragment (Mb VLVH) | FC, ELISA | Human antibody |
TAB-337LC-F(E) | Anti-Human CD70 Recombinant Antibody Fab Fragment (Mb VHVL) | FC, ELISA | Human antibody |
TAB-338LC-F(E) | Anti-Human CD70 Recombinant Antibody Fab Fragment (VL-5-VH) | FC, ELISA | Human antibody |
TAB-339LC-F(E) | Anti-Human CD70 Recombinant Antibody Fab Fragment (VH-5-VL) | FC, ELISA | Human antibody |
TAB-340LC-F(E) | Anti-Human CD70 Recombinant Antibody Fab Fragment (VL-8-VH) | FC, ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-403CQ | Rat Anti-Cd70 Recombinant Antibody (clone 9G24) | ELISA, Neut | Rat IgG1 |
NEUT-405CQ | Rat Anti-Cd70 Recombinant Antibody (clone CBL684) | ELISA, Neut | Rat IgG1 |
NEUT-406CQ | Rat Anti-Cd70 Recombinant Antibody (clone FR70) | FC, FuncS, Neut, IP | Rat IgG2b, κ |
NEUT-407CQ | Rat Anti-Cd70 Recombinant Antibody (clone CBL856) | ELISA, Neut | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-404CQ | Rat Anti-Cd70 Recombinant Antibody (clone MAB0825) | Block, FC, Inhib, IP | Rat IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0095-LSX | Human Anti-CD70 Recombinant Antibody (HPAB-0095-LSX) | ELISA, FC, ADCC, FuncS | Human IgG |
HPAB-0096-LSX | Human Anti-CD70 Recombinant Antibody (HPAB-0096-LSX) | ELISA, FC, Block, FuncS | Human IgG |
HPAB-0097-LSX | Human Anti-CD70 Recombinant Antibody (HPAB-0097-LSX) | ELISA, FC, Block, FuncS | Human IgG |
HPAB-0099-LSX | Human Anti-CD70 Recombinant Antibody (HPAB-0099-LSX) | ELISA, FC, Block | Human IgG |
HPAB-0100-LSX | Human Anti-CD70 Recombinant Antibody (HPAB-0100-LSX) | ELISA, Inhib, ADCC, ADCP, CDC, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0095-LSX-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0095-LSX-S(P)) | ELISA, FC | Human scFv |
HPAB-0096-LSX-S(P) | Human Anti-CD70 Recombinant Antibody; scFv Fragment (HPAB-0096-LSX-S(P)) | ELISA, FC | Human scFv |
HPAB-M0487-YC-S(P) | Rat Anti-CD70 Recombinant Antibody (clone 4F2-12); scFv Fragment | FC | Rat scFv |
HPAB-AP588-YC-S(P) | Human Anti-CD70 Recombinant Antibody (clone h1F6-HJLA); scFv Fragment | FC, ADCC, CDC, FuncS | Humanized (mouse/human) scFv |
HPAB-AP589-YC-S(P) | Human Anti-CD70 Recombinant Antibody (clone h1F6-HMLA); scFv Fragment | ELISA, Cyt, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-H76 | Afuco™ Anti-CD70 ADCC Recombinant Antibody (Vorsetuzumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0468-WJ-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0468-WJ-F(E)) | ELISA | Human Fab |
HPAB-0469-WJ-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0469-WJ-F(E)) | ELISA | Human Fab |
HPAB-0470-WJ-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0470-WJ-F(E)) | ELISA | Human Fab |
HPAB-0471-WJ-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0471-WJ-F(E)) | ELISA | Human Fab |
HPAB-0472-WJ-F(E) | Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0472-WJ-F(E)) | ELISA | Human Fab |
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