Afuco™ Anti-Human CDH11 ADCC Recombinant Antibody (SDP051), ADCC Enhanced (CAT#: AFC-142CL)
Anti-CDH11 ADCC Enhanced Antibody (SDP051) is an ADCC enhanced antibody produced by our Afuco™ platform. This is a humanized monoclonal antibody to Cadherin-11, which acts as an "adhesive" between cells. Changes in Cad-11 interactions can induce cells to produce proteins that influence the cellular environment. Results from the Phase 1 trial show that SDP051 is safe and well-tolerated at doses up to 10 mg/kg per day with no evidence of significant side effects.
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ELISA
Figure 1 Afuco™ Anti-Human CDH11 ADCC Theraputic Antibody (SDP051) (AFC-142CL) in ELISA
ELISA analysis of AFC-142CL was performed by coating with Recombinant Human CDH11 Fc Chimera.
WB
Figure 2 Afuco™ Anti-Human CDH11 ADCC Theraputic Antibody (SDP051) (AFC-142CL) in WB
Lane M: Marker
Lane 1: Recombinant Human CDH11 Fc Chimera (50 ng)
Lane 2: Recombinant Human CDH11 Fc Chimera (200 ng)
Lane 3: Recombinant Human CDH11 Fc Chimera (600 ng)
Lane 4: Control
Primary antibody: AFC-142CL-Biotin
Secondary antibody: SA-HRP
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Rheumatoid Arthritis
Product Property
- Purity
- >95% by HPLC
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- CDH11; cadherin 11, type 2, OB-cadherin (osteoblast); OB; CAD11; CDHOB; OSF-4; cadherin 11; cadherin-1
- Gene ID
- 1009
- UniProt ID
- P55287
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Single Domain Antibody Products
Humanized Antibody Products
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-514-sdAb | Recombinant Anti-Human CDH11 VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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