Afuco™ Anti-Human CDH11 ADCC Recombinant Antibody (SDP051), ADCC Enhanced (CAT#: AFC-142CL)
Anti-CDH11 ADCC Enhanced Antibody (SDP051) is an ADCC enhanced antibody produced by our Afuco™ platform. This is a humanized monoclonal antibody to Cadherin-11, which acts as an "adhesive" between cells. Changes in Cad-11 interactions can induce cells to produce proteins that influence the cellular environment. Results from the Phase 1 trial show that SDP051 is safe and well-tolerated at doses up to 10 mg/kg per day with no evidence of significant side effects.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 Afuco™ Anti-Human CDH11 ADCC Theraputic Antibody (SDP051) (AFC-142CL) in ELISA
ELISA analysis of AFC-142CL was performed by coating with Recombinant Human CDH11 Fc Chimera.
WB
Figure 2 Afuco™ Anti-Human CDH11 ADCC Theraputic Antibody (SDP051) (AFC-142CL) in WB
Lane M: Marker
Lane 1: Recombinant Human CDH11 Fc Chimera (50 ng)
Lane 2: Recombinant Human CDH11 Fc Chimera (200 ng)
Lane 3: Recombinant Human CDH11 Fc Chimera (600 ng)
Lane 4: Control
Primary antibody: AFC-142CL-Biotin
Secondary antibody: SA-HRP
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Rheumatoid Arthritis
Product Property
- Purity
- >95% by HPLC
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- CDH11; cadherin 11, type 2, OB-cadherin (osteoblast); OB; CAD11; CDHOB; OSF-4; cadherin 11; cadherin-1
- Gene ID
- 1009
- UniProt ID
- P55287
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-514-sdAb | Recombinant Anti-Human CDH11 VHH Single Domain Antibody | ICC, FC, WB, FUNC | Llama VHH |
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