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    Mouse Anti-CDH11 Recombinant Antibody (TAB-1412CL) (CAT#: TAB-1412CL)

    The antibody exhibits specific binding to the EC1 domain of Cadherin-11. EC 1 antibody H1M1 binds Cad-11-EC1-Fc fusion protein and Cad-11-EC1-5-Fc fusion protein. It suppresses arthritis-related joint swelling in vivo in a mouse model of rheumatoid arthritis.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_B_9_5.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_A_8_3.jpg
    Figure 3 Kidney
    Figure 3 Kidney
    (Cells in glomeruli
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_A_7_5.jpg
    Figure 4 Breast
    Figure 4 Breast
    (Glandular cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Myoepithelial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13072/32893_B_2_4.jpg
    RNA Expression
    Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HSkMC, PC-3, U-2197)
    Figure 5 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+, fHDF/TERT166, HSkMC, PC-3, U-2197)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140937-CDH11

    Specifications

    • Immunogen
    • Mouse Cadherin-11-Fc fusion protein
    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • Human Cadherin-11
    • Species Reactivity
    • Human
    • Applications
    • ELISA, FuncS
    • Related Disease
    • Cadherin-11-mediated disorders including inflammatory disorders (e.g., inflammatory joint disorders, such as rheumatoid arthritis), fibrosis and cancer

    Product Property

    • Purity
    • >95% as determined by SDS-PAGE
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Preservative
    • No preservatives
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • CDH11; cadherin 11, type 2, OB-cadherin (osteoblast); OB; CAD11; CDHOB; OSF-4; cadherin 11; cadherin-1

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CDH11"

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    CAT Product Name Application Type
    NAB-514-sdAb Recombinant Anti-Human CDH11 VHH Single Domain Antibody ICC, FC, WB, FUNC Llama VHH

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