Recombinant Mouse Antibody (T84.66) is capable of binding to CEA, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 ELISA measurements of FcγR binding to scFv-Fc variants.
Bind-ing of mFcγRI to titratedamounts of T84.66 and the scFv-Fc variants (WT, I253A, H310A, and H435Q). The numbers given represent the mean of triplicates.
Andersen, J. T., Foss, S., Kenanova, V. E., Olafsen, T., Leikfoss, I. S., Roopenian, D. C., ... & Sandlie, I. (2012). Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life. Journal of Biological Chemistry, 287(27), 22927-22937.
Figure 2 SPR analyses of the interaction of chimeric anti-CEA T84.66 IgG1 with mFcRn and hFcRn.
Representative sensorgrams show serial dilutions of anti-CEA T84.66 IgG1(0.004-1μM) injected over a flow cell coupledwith mFcRn (~300 RU) at a flow rate of 50l/min (pH6.0).
Andersen, J. T., Foss, S., Kenanova, V. E., Olafsen, T., Leikfoss, I. S., Roopenian, D. C., ... & Sandlie, I. (2012). Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life. Journal of Biological Chemistry, 287(27), 22927-22937.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-037 | Mouse Anti-CEA Recombinant Antibody (clone MFE-23) | ELISA, WB, FuncS | Mouse IgG |
HPAB-0539-WJ | Mouse Anti-CEA Recombinant Antibody (clone COL-1) | ELISA | Mouse IgG |
HPAB-0540-WJ | Human Anti-CEA Recombinant Antibody (clone HuCOL-1) | ELISA | Humanized IgG |
HPAB-0541-WJ | Mouse Anti-CEA Recombinant Antibody (clone 806.077) | ELISA | Mouse IgG |
HPAB-0542-WJ | Human Anti-CEA Recombinant Antibody (clone Hu806.077) | ELISA | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0059-YC-S(P) | Mouse Anti-CEA Recombinant Antibody (clone 2-18); scFv Fragment | IF, FuncS | Mouse scFv |
HPAB-0631-YJ-S(P) | Mouse Anti-CEA Recombinant Antibody (clone F33-104); scFv Fragment | ELISA, WB | Mouse scFv |
FAMAB-0083JF-S(P) | Mouse Anti-CEA Recombinant Antibody (clone C1); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
FAMAB-0084JF-S(P) | Mouse Anti-CEA Recombinant Antibody (clone C5); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
FAMAB-0085JF-S(P) | Mouse Anti-CEA Recombinant Antibody (clone C7); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0059-YC-F(E) | Mouse Anti-CEA Recombinant Antibody (clone 2-18); Fab Fragment | IF, FuncS | Mouse Fab |
FAMAB-0060-YC-F(E) | Human Anti-CEA Recombinant Antibody (clone ch2-18); Fab Fragment | IF, FuncS | Human Fab |
FAMAB-0061-YC-F(E) | Mouse Anti-CEA Recombinant Antibody (clone Fll-35); Fab Fragment | IP, FuncS | Mouse Fab |
FAMAB-0062-YC-F(E) | Mouse Anti-CEA Recombinant Antibody (clone Fl1-39); Fab Fragment | IP, FuncS | Mouse Fab |
FAMAB-0063-YC-F(E) | Human Anti-CEA Recombinant Antibody (clone Ch F11-35); Fab Fragment | IP, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP500-YC | Recombinant Camel Anti-CEA Single Domain Antibody (ASEAN-1) | ELISA | Camel VHH |
HPAB-1210WJ | Recombinant Dromedary Anti-CEA Single Domain Antibody (CEA1) | ELISA | Dromedary VHH |
HPAB-1211WJ | Recombinant Dromedary Anti-CEA Single Domain Antibody (CEA72) | ELISA | Dromedary VHH |
HPAB-0698-YJ-VHH | Camelid Anti-CEA Recombinant Single Domain Antibody (C17) | ELISA, FC, In vivo staining | Camelid VHH |
HPAB-0699-YJ-VHH | Camelid Anti-CEA Recombinant Single Domain Antibody (C43) | ELISA, FC, In vivo staining | Camelid VHH |
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