Mouse Anti-CEA Recombinant Antibody (clone T84.66) (CAT#: PABL-038)
Recombinant Mouse Antibody (T84.66) is capable of binding to CEA, expressed in Chinese Hamster Ovary cells (CHO).
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Custom Production
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ELISA
Figure 1 ELISA measurements of FcγR binding to scFv-Fc variants.
Bind-ing of mFcγRI to titratedamounts of T84.66 and the scFv-Fc variants (WT, I253A, H310A, and H435Q). The numbers given represent the mean of triplicates.
Andersen, J. T., Foss, S., Kenanova, V. E., Olafsen, T., Leikfoss, I. S., Roopenian, D. C., ... & Sandlie, I. (2012). Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life. Journal of Biological Chemistry, 287(27), 22927-22937.
FuncS
Figure 2 SPR analyses of the interaction of chimeric anti-CEA T84.66 IgG1 with mFcRn and hFcRn.
Representative sensorgrams show serial dilutions of anti-CEA T84.66 IgG1(0.004-1μM) injected over a flow cell coupledwith mFcRn (~300 RU) at a flow rate of 50l/min (pH6.0).
Andersen, J. T., Foss, S., Kenanova, V. E., Olafsen, T., Leikfoss, I. S., Roopenian, D. C., ... & Sandlie, I. (2012). Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life. Journal of Biological Chemistry, 287(27), 22927-22937.
Specifications
- Immunogen
- Human Carcinoembryonic Antigen
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CEA
- Species Reactivity
- Human
- Clone
- T84.66
- Applications
- ELISA, WB, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay and Function Assay.
Target
- Alternative Names
- CEA; Carcinoembryonic Antigen
- Gene ID
- 1048
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0059YC | Mouse Anti-CEA Recombinant Antibody (clone 2-18) | IF, FuncS | Mouse IgG1, κ |
| FAMAB-0060YC | Human Anti-CEA Recombinant Antibody (clone ch2-18) | IF, FuncS | Chimeric (mouse/human) IgG |
| FAMAB-0061YC | Mouse Anti-CEA Recombinant Antibody (clone Fll-35) | IP, FuncS | Mouse IgG |
| FAMAB-0062YC | Mouse Anti-CEA Recombinant Antibody (clone Fl1-39) | IP, FuncS | Mouse IgG |
| FAMAB-0063YC | Human Anti-CEA Recombinant Antibody (clone Ch F11-35) | IP, FuncS | Chimeric (mouse/human) IgG1, κ |
Customer Reviews and Q&As
Customer Review
Q&As
Excellent client service
We had an excellent experience with this product because of the excellent customer service we received, which included timely responses and useful recommendations.
Easy to use
This antibody product's user-friendly design and straightforward instructions make it simple to integrate it hassle-free into our current methods.
elevated sensitivity
Because of this antibody product's excellent sensitivity, we can confidently identify even targets with low abundance.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABL-038, RRID: AB_3111623)
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For Research Use Only. Not For Clinical Use.
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