Human Anti-CHRM2 Recombinant Antibody (clone P90-131); scFv Fragment (CAT#: NS-058CN-S(P))
Anti-AchR antibody P90-131 is a human monoclonal antibody direct against the gamma subunit of the acetylcholine receptor, which can be used in the treatment of rhabdomyosarcomas.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(ndothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_B_8_5.jpg
(ndothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_B_8_5.jpg
Figure 2 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_8_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_8_3.jpg
Figure 3 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_9_4.jpg
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_9_4.jpg
Figure 4 Kidney
(Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_7_5.jpg
(Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_7_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_6_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_6_6.jpg
Figure 6 Heart muscle
(Cardiomyocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29795/62923_B_6_6.jpg
(Cardiomyocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29795/62923_B_6_6.jpg
Figure 7 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_7_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/22338/62925_A_7_8.jpg
Figure 8 RNA cell line category: Cell line enriched (fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181072-CHRM2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000181072-CHRM2
Specifications
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human CHRM2
- Species Reactivity
- Human
- Clone
- P90-131
- Applications
- RIA, ELISA, WB, IP, IF
- Related Disease
- Rhabdomyosarcomas
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cholinergic Receptor, Muscarinic 2; Acetylcholine Receptor, Muscarinic 2; Acetylcholine Receptor; Muscarinic M2 Receptor; Muscarinic 2; 7TM Receptor; HM2
- Gene ID
- 1129
- UniProt ID
- P08172
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone P90-131"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-205 | Recombinant Anti-human CHRM2 Antibody | ELISA, WB, IP, FuncS | IgG |
| MHH-205 | Recombinant Human Anti-human CHRM2 Antibody | ELISA, WB, FC, FuncS | IgG |
| VS3-QX236 | Mouse Anti-CHRM2 Recombinant Antibody (clone 1424CT461.78.60) | ICC, IHC, FC | Mouse IgG1, κ |
| VS3-CJ487 | Mouse Anti-CHRM2 Recombinant Antibody (VS3-CJ487) | WB, IF, IHC-P, FC | Mouse IgG1, κ |
| VS3-FY383 | Recombinant Rabbit Anti-CHRM2 Antibody (clone R01-9B9) | WB, IHC-P, IP | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-205-F(E) | Recombinant Anti-human CHRM2 Antibody Fab Fragment | WB, IF, FuncS | Fab |
| MHH-205-F(E) | Recombinant Human Anti-human CHRM2 Antibody Fab Fragment | IP, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-205-S(P) | Recombinant Anti-human CHRM2 Antibody scFv Fragment | FC, Neut, Biosensors, FuncS | scFv |
| MHH-205-S(P) | Recombinant Human Anti-human CHRM2 Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-081 | Recombinant Anti-human CHRM2 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
| HPAB-0354-YJ-VHH | Recombinant Llama Anti-CHRM2 Single Domain Antibody (HPAB-0354-YJ-VHH) | FC | Llama VHH |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0697 | Hi-Affi™ Rabbit Anti-CHRM2 Recombinant Antibody (clone DS697AB) | WB, IHC, ICC, IP | Rabbit IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-058CN | Human Anti-CHRM2 Recombinant Antibody (clone P90-131) | RIA, ELISA, WB, IP, IF | Human IgG |
| NS-058CN-F(E) | Human Anti-CHRM2 Recombinant Antibody (clone P90-131); Fab Fragment | RIA, ELISA, WB, IP, IF | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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