Afuco™ Anti-Human CLDN6 ADCC Recombinant Antibody (IMAB 027), ADCC Enhanced
CAT#: AFC-160CL
Anti-CLDN6 ADCC Enhanced Antibody (IMAB 027) is an ADCC enhanced antibody produced by our Afuco™ platform. IMAB027 is a first-in-class monoclonal antibody selectively binding to the cell surface protein Claudin-6 (CLDN6) which is present in a wide range of cancers, including testicular, ovarian, uterine, and lung cancers. A key advantage of IMAB027 is that CLDN6 is an embryonic antigen which is absent from healthy adult tissue. This unmatched tumor cell specificity of CLDN6 makes IMAB027 a cancer cell selective drug allowing it to efficiently kill tumor cells without harming healthy non-cancerous cells.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (BEWO, CACO-2, NTERA-2, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184697-CLDN6
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Specifications
- Host Species
- Chimeric
- Derivation
- Chimeric
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Ovarian Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- 4 °C, -20°C if preferred
Target
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(Creative Biolabs Cat# AFC-160CL, RRID: AB_3111277)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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See other products for "CLDN6"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3290z | Mouse Anti-CLDN6 Recombinant Antibody (clone 21D9) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| HPAB-0078-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-0078-FY) | Activ | Mouse IgG2a, κ |
| HPAB-1496-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-1496-FY) | ELISA, FC | Mouse IgG2a, κ |
| HPAB-1497-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-1497-FY) | ELISA, FC | Mouse IgG2a, κ |
| VS7-HM748 | Mouse Anti-CLDN6 Recombinant Antibody (clone 8G5D2) | FCM | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-507LC-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (TAB-507LC-S(P)) | FC, IHC | Mouse scFv |
| TAB-507LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-507LC-F(E)) | FC, IHC | Mouse Fab |
| TAB-508LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-508LC-F(E)) | FC, IHC | Mouse Fab |
| TAB-509LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-509LC-F(E)) | FC, IHC | Mouse Fab |
| TAB-510LC-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (TAB-510LC-F(E)) | FC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-FY-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (HPAB-0078-FY-S(P)) | Activ | Mouse scFv |
| HPAB-1496-FY-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (HPAB-1496-FY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-1497-FY-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (HPAB-1497-FY-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0078-FY-F(E) | Mouse Anti-CLDN6 Recombinant Antibody; Fab Fragment (HPAB-0078-FY-F(E)) | Activ | Mouse Fab |
| HPAB-1496-FY-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (HPAB-1496-FY-S(P)) | ELISA, FC | Mouse scFv |
| HPAB-1497-FY-S(P) | Mouse Anti-CLDN6 Recombinant Antibody; scFv Fragment (HPAB-1497-FY-S(P)) | ELISA, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC130 | Recombinant Anti-CLDN6 Vesicular Antibody, EV Displayed (VS-0425-YC130) | Cyt, ELISA, FC, Cell-uptake |
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