Afuco™ Anti-Human CLDN6 ADCC Recombinant Antibody (IMAB 027), ADCC Enhanced (CAT#: AFC-160CL)
Anti-CLDN6 ADCC Enhanced Antibody (IMAB 027) is an ADCC enhanced antibody produced by our Afuco™ platform. IMAB027 is a first-in-class monoclonal antibody selectively binding to the cell surface protein Claudin-6 (CLDN6) which is present in a wide range of cancers, including testicular, ovarian, uterine, and lung cancers. A key advantage of IMAB027 is that CLDN6 is an embryonic antigen which is absent from healthy adult tissue. This unmatched tumor cell specificity of CLDN6 makes IMAB027 a cancer cell selective drug allowing it to efficiently kill tumor cells without harming healthy non-cancerous cells.
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RNA Expression
Figure 1 RNA cell line category: Group enriched (BEWO, CACO-2, NTERA-2, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184697-CLDN6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000184697-CLDN6
Specifications
- Host Species
- Chimeric
- Derivation
- Chimeric
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Ovarian Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- 4 °C, -20°C if preferred
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Mouse Antibody Products
ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3290z | Mouse Anti-CLDN6 Recombinant Antibody (clone 21D9) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| HPAB-0078-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-0078-FY) | Activ | Mouse IgG2a, κ |
| HPAB-1496-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-1496-FY) | ELISA, FC | Mouse IgG2a, κ |
| HPAB-1497-FY | Mouse Anti-CLDN6 Recombinant Antibody (HPAB-1497-FY) | ELISA, FC | Mouse IgG2a, κ |
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# AFC-160CL, RRID: AB_3111277)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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