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Anti-Human CNR1 Recombinant Antibody (RYI-018) (CAT#: TAB-181CL)

Recombinant monoclonal antibody expressed in CHO binding to Human CNR1. This is a first in class functional antagonist of Cannabinoid 1 Receptor (CB1), under preclinical development for metabolic and fibrotic indications, NASH, liver fibrosis, kidney fibrosis, metabolic disease.


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Subcellular Location
Figure 1 IF staining of human cell line AF22
Figure 1 IF staining of human cell line AF22
(Immunofluorescent staining of human cell line AF22 shows localization to plasma membrane & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42256/1595_A8_2_selected.jpg
Normal Tissue
Figure 2 Low expression in liver
Figure 2 Low expression in liver

* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69945/166905_A_7_4_val_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69945/166905_B_8_5.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69945/166905_A_7_3.jpg
Figure 5 Testis
Figure 5 Testis
(Sertoli cells Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69945/166905_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (ASC diff, HSkMC)
Figure 6 RNA cell line category: Group enriched (ASC diff, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000118432-CNR1

Specifications

  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Metabolic Disease

Product Property

  • Purity
  • >95% as determined by analysis by RP-HPLC
  • Storage
  • Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.

Target

  • Alternative Names
  • CNR1; cannabinoid receptor 1 (brain); CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5; cannabinoid receptor 1; central cannabinoid receptor

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "CNR1"

Human Antibody

CAT Product Name Application Type
TAB-1492CL Human Anti-CNR1 Recombinant Antibody (TAB-1492CL) FC, FuncS Human IgG
TAB-1492CL-S(P) Human Anti-CNR1 Recombinant Antibody; scFv Fragment (TAB-1492CL-S(P)) FC, FuncS Human scFv
TAB-1492CL-F(E) Human Anti-CNR1 Recombinant Antibody; Fab Fragment (TAB-1492CL-F(E)) FC, FuncS Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0122-YJ-S(P) Mouse Anti-CNR1 Recombinant Antibody; scFv Fragment (HPAB-0122-YJ-S(P)) ELISA, FC, FuncS Mouse scFv
HPAB-0123-YJ-S(P) Human Anti-CNR1 Recombinant Antibody; scFv Fragment (HPAB-0123-YJ-S(P)) ELISA, FC, FuncS Human scFv
HPAB-0124-YJ-S(P) Human Anti-CNR1 Recombinant Antibody; scFv Fragment (HPAB-0124-YJ-S(P)) ELISA, FC, FuncS Human scFv
HPAB-2987LY-S(P) Mouse Anti-CNR1 Recombinant Antibody; scFv Fragment (HPAB-2987LY-S(P)) ELISA, WB, FC, FuncS Mouse scFv
HPAB-3025LY-S(P) Mouse Anti-CNR1 Recombinant Antibody; scFv Fragment (HPAB-3025LY-S(P)) ELISA, WB, FC, FuncS Mouse scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0122-YJ-F(E) Mouse Anti-CNR1 Recombinant Antibody; Fab Fragment (HPAB-0122-YJ-F(E)) ELISA, FC, FuncS Mouse Fab
HPAB-0123-YJ-F(E) Human Anti-CNR1 Recombinant Antibody; Fab Fragment (HPAB-0123-YJ-F(E)) ELISA, FC, FuncS Human Fab
HPAB-0124-YJ-F(E) Human Anti-CNR1 Recombinant Antibody; Fab Fragment (HPAB-0124-YJ-F(E)) ELISA, FC, FuncS Human Fab
HPAB-2991LY-F(E) Human Anti-CNR1 Recombinant Antibody; Fab Fragment (HPAB-2991LY-F(E)) ELISA, WB, FC, FuncS Chimeric (mouse/human) Fab
HPAB-2992LY-F(E) Human Anti-CNR1 Recombinant Antibody; Fab Fragment (HPAB-2992LY-F(E)) ELISA, WB, FC, FuncS Chimeric (mouse/human) Fab

Recombinant Antibody

CAT Product Name Application Type
HPAB-2987LY Human Anti-CNR1 Recombinant Antibody (HPAB-2987LY) ELISA, WB, FC, FuncS Chimeric (mouse/human) IgG
HPAB-2988LY Human Anti-CNR1 Recombinant Antibody (HPAB-2988LY) ELISA, WB, FC, FuncS Chimeric (mouse/human) IgG
HPAB-2989LY Human Anti-CNR1 Recombinant Antibody (HPAB-2989LY) ELISA, WB, FC, FuncS Chimeric (mouse/human) IgG
HPAB-2990LY Human Anti-CNR1 Recombinant Antibody (HPAB-2990LY) ELISA, WB, FC, FuncS Chimeric (mouse/human) IgG
HPAB-2991LY Human Anti-CNR1 Recombinant Antibody (HPAB-2991LY) ELISA, WB, FC, FuncS Chimeric (mouse/human) IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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