Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9) (CAT#: HPAB-0423-CN)
EDI19E9 is an immunogenicity-reduced antibody against the human erythrocyte complement receptor 1 (CR1). EDI19E9 comprises several amino acid substitutions so that the immunogenicity-reduced antibody is non-immunogenic or less immunogenic to a human.
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Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
Figure 3 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
Figure 4 RNA cell line category: Group enriched (HL-60, HMC-1, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human CR1
- Species Reactivity
- Human
- Clone
- EDI19E9
- Applications
- ELISA, FC
- Related Disease
- Diseases caused by a blood-borne immunogenic pathogen
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Knops Blood Group Antigen; C3-Binding Protein; C4BR; CD35; KN
- Gene ID
- 1378
- UniProt ID
- P17927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0284MZ | Recombinant Mouse Anti-Human Complement Component (3b/4b) Receptor 1 (Knops blood group) Antibody (clone Cer-MAC-DRC1) | IHC | Mouse antibody |
| HPAB-J0316-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0316-YC) | ELISA | Human HC IgG2 |
| HPAB-J0317-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0317-YC) | ELISA | Human HC IgG3 |
| ZG-0107J | Mouse Anti-CR1 Recombinant Antibody (ZG-0107J) | IHC-P, IF | Mouse IgG |
| ZG-0108J | Mouse Anti-CR1 Recombinant Antibody (ZG-0108J) | IHC-P, IF | Mouse IgG |
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