Mouse Anti-CR1 Recombinant Antibody (clone EDI19E9); scFv Fragment (CAT#: HPAB-0423-CN-S(P))
EDI19E9 is an immunogenicity-reduced antibody against the human erythrocyte complement receptor 1 (CR1). EDI19E9 comprises several amino acid substitutions so that the immunogenicity-reduced antibody is non-immunogenic or less immunogenic to a human.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_9_5.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_8_8.jpg
Figure 3 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49348/115721_A_4_8.jpg
Figure 4 RNA cell line category: Group enriched (HL-60, HMC-1, NB-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000203710-CR1
Specifications
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human CR1
- Species Reactivity
- Human
- Clone
- EDI19E9
- Applications
- ELISA, FC
- Related Disease
- Diseases caused by a blood-borne immunogenic pathogen
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Complement Component (3b/4b) Receptor 1 (Knops Blood Group); C3b/C4b Receptor; CD35 Antigen; C3BR; Complement Component (3b/4b) Receptor 1, Including Knops Blood Group System; Knops Blood Group Antigen; C3-Binding Protein; C4BR; CD35; KN
- Gene ID
- 1378
- UniProt ID
- P17927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-240 | Recombinant Anti-human CR1 Antibody | ELISA, WB, IF, FuncS | IgG |
| MOB-0284MZ | Recombinant Mouse Anti-Human Complement Component (3b/4b) Receptor 1 (Knops blood group) Antibody (clone Cer-MAC-DRC1) | IHC | Mouse antibody |
| HPAB-J0316-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0316-YC) | ELISA | Human HC IgG2 |
| HPAB-J0317-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0317-YC) | ELISA | Human HC IgG3 |
| HPAB-J0318-YC | Human Anti-CR1 Recombinant Antibody (HPAB-J0318-YC) | ELISA | Human HC IgG2 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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