Mouse Anti-CSF2RB Recombinant Antibody (clone BION-1) (CAT#: PABZ-029)
Recombinant Mouse Antibody (BION-1) is capable of binding to CSF2RB, expressed in Chinese Hamster Ovary cells (CHO). BION-1 binds 3 known eosinophil-producing cytokines of the GM-CSF/IL-3/IL-5 receptor beta-chain (beta(c) signaling subunit.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HUVEC TERT2
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78677/1751_C10_13_cr57fd269edaa96_selected.jpg
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78677/1751_C10_13_cr57fd269edaa96_selected.jpg
Figure 2 RNA cell line category: Group enriched (HEL, HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100368-CSF2RB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100368-CSF2RB
Specifications
- Immunogen
- Human colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CSF2RB
- Species Reactivity
- Human
- Clone
- BION-1
- Applications
- Block, IP
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody BION-1 has been reported in applications of Flow Cytometry, Western Blot, Functional Assay, Blocking, Inhibition, Immunoprecipitation. It's recommended that the optimal antibody concentration, dilution, incubition time etc. are best to be carefully titrated in specific assays.
Blocking: This antibody has been tested for blocking high-affinity binding of IL-5, GM-CSF, and IL-3 to human eosinophils. 1.8 × 10^6 Human eosinophils were needed and the concentration of BION-1 was 1 μmol/L.
Target
- Alternative Names
- CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); CD131; IL3RB; IL5RB; SMDP5; CDw131; cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity);
- Gene ID
- 1439
- UniProt ID
- P32927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-029 | Mouse Anti-CSF2RB Recombinant Antibody (clone BION-1); Fab Fragment | Block, IP | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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