Mouse Anti-CXCR5 Recombinant Antibody (clone 2C9) (CAT#: HPAB-0109-LSX)
Recombinant monoclonal antibody to CXCR5. Clone 2C9 is a mouse monoclonal antibody that can be potentially used in the treatment of Rheumatoid arthritis (RA).
Specific Inquiry
ELISA
Figure 1 Representative experiment of the concentration dependent binding of purified murine anti-CXCR5 antibody 2C9 to CHOal6 cells expressing human CXCR5 in cell ELISA.
Murine anti-CXCR5 antibody 2C9 did not bind to parental CHOal6 cells
Inhib
Figure 2 The inhibition of CXCL13 induced Ca-flux in CHOocl6 cells expressing human CXCR5 by purified murine anti-CXCR5 antibody 2C9.
Figure 3 Murine anti-CXCR5 antibody 2C9 does not stimulate the Ca-flux in CHOal6 cells expressing human CXCR5 by itself whereas 30 nM CXCL13 stimulates Ca-flux.
Specifications
- Immunogen
- Human CXCR5
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human CXCR5
- Species Reactivity
- Human
- Clone
- 2C9
- Applications
- ELISA, WB, Inhib
- Related Disease
- Rheumatoid arthritis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-Linked Immunosorbent Assay and Inhibition.
Target
- Alternative Names
- Chemokine (C-X-C Motif) Receptor 5; Burkitt Lymphoma Receptor 1, GTP Binding Protein (Chemokine (C-X-C Motif) Receptor 5); Burkitt Lymphoma Receptor 1, GTP-Binding Protein; Monocyte-Derived Receptor 15; CXC-R5; CXCR-5; MDR-15; MDR15; BLR1; Burkitt Lymphoma Receptor 1; CD185 Antigen; CD185
- Gene ID
- 643
- UniProt ID
- P32302
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1702z | Mouse Anti-CXCR5 Recombinant Antibody (clone 28C11) | FC, ICC, IHC, Neut | Mouse IgG2b |
| MOB-2070MZ | Recombinant Mouse Anti-Human CXCR5 Antibody (clone 62606.222) | FC | Mouse antibody |
| HPAB-0110-LSX | Human Anti-CXCR5 Recombinant Antibody (clone H4BL2) | ELISA, WB, FC, Dep | Human IgG |
| MRO-0406-CN | Rabbit Anti-CXCR5 Recombinant Antibody (clone JB11-40) | WB, IHC, FC | Rabbit IgG |
| VS-0723-WK68 | Human Anti-CXCR5 Recombinant Antibody (VS-0723-WK68) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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