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    Anti-Human CXCR5 Recombinant Antibody (m2C9) (CAT#: TAB-161MZ)

    This antibody that specifically binds to human CXCR5 may be used for the treatment of rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, and other B-cell-dependent autoimmune diseases.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    ELISA

    Figure 1 shows a representative experiment of the concentration dependent binding of purified murine anti-CXCR5 antibody 2C9 to CHOal6 cells expressing human CXCR5 in cell ELISA.

    Figure 1 shows a representative experiment of the concentration dependent binding of purified murine anti-CXCR5 antibody 2C9 to CHOal6 cells expressing human CXCR5 in cell ELISA.

    FC

    Figure 2 shows the binding of the humanized antibodies.

    Figure 2 shows the binding of the humanized antibodies.

    Daudi target cells were incubated with the antibodies and binding was detected using a fluorescently labeled secondary antibody and subsequent analysis via flow cytometry (FACS)

    Inhib

    Figure 3 shows the inhibition of CXCL13 (50 nM) induced Ca- mobilization by humanized, glycoengineered anti-CXCR5 antibody

    Figure 3 shows the inhibition of CXCL13 (50 nM) induced Ca- mobilization by humanized, glycoengineered anti-CXCR5 antibody

    FuncS

    Figure 4 shows the depleting activity of different humanized, glycoengineered antibodies.

    Figure 4 shows the depleting activity of different humanized, glycoengineered antibodies.


    Specifications

    • Immunogen
    • Murine LI .2 cells recombinantly expressing human CXCR5
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Clone
    • m2C9
    • Applications
    • ELISA, FC, FuncS, Inhib
    • Related Disease
    • Rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, and other B-cell-dependent autoimmune diseases

    Applications

    • Application Notes
    • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Functional Assay, Inhibition.

    Target

    • Alternative Names
    • CXCR5; chemokine (C-X-C motif) receptor 5; BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone m2C9"

    See other products for "CXCR5"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Human Antibody Products Mouse Antibody Products Humanized Antibody Products Fc Glycosylation Antibody Products Low- or Non-fucosylated Oligosaccharide Antibody Products Neutralizing Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-1702z Mouse Anti-CXCR5 Recombinant Antibody (clone 28C11) FC, ICC, IHC, Neut Mouse IgG2b
    MOB-2070MZ Recombinant Mouse Anti-Human CXCR5 Antibody (clone 62606.222) FC Mouse antibody
    HPAB-0109-LSX Mouse Anti-CXCR5 Recombinant Antibody (clone 2C9) ELISA, WB, Inhib Mouse IgG
    HPAB-0110-LSX Human Anti-CXCR5 Recombinant Antibody (clone H4BL2) ELISA, WB, FC, Dep Human IgG
    MRO-0406-CN Rabbit Anti-CXCR5 Recombinant Antibody (clone JB11-40) WB, IHC, FC Rabbit IgG

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