Anti-Human CXCR5 Recombinant Antibody (m2C9) (CAT#: TAB-161MZ)
This antibody that specifically binds to human CXCR5 may be used for the treatment of rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, and other B-cell-dependent autoimmune diseases.
Specific Inquiry
ELISA
Figure 1 shows a representative experiment of the concentration dependent binding of purified murine anti-CXCR5 antibody 2C9 to CHOal6 cells expressing human CXCR5 in cell ELISA.
FC
Figure 2 shows the binding of the humanized antibodies.
Daudi target cells were incubated with the antibodies and binding was detected using a fluorescently labeled secondary antibody and subsequent analysis via flow cytometry (FACS)
Inhib
Figure 3 shows the inhibition of CXCL13 (50 nM) induced Ca- mobilization by humanized, glycoengineered anti-CXCR5 antibody
FuncS
Figure 4 shows the depleting activity of different humanized, glycoengineered antibodies.
Specifications
- Immunogen
- Murine LI .2 cells recombinantly expressing human CXCR5
- Host Species
- Mouse
- Specificity
- Human
- Clone
- m2C9
- Applications
- ELISA, FC, FuncS, Inhib
- Related Disease
- Rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, and other B-cell-dependent autoimmune diseases
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Functional Assay, Inhibition.
Target
- Alternative Names
- CXCR5; chemokine (C-X-C motif) receptor 5; BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
- Gene ID
- 643
- UniProt ID
- A0N0R2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1702z | Mouse Anti-CXCR5 Recombinant Antibody (clone 28C11) | FC, ICC, IHC, Neut | Mouse IgG2b |
| MOB-2070MZ | Recombinant Mouse Anti-Human CXCR5 Antibody (clone 62606.222) | FC | Mouse antibody |
| MRO-0406-CN | Rabbit Anti-CXCR5 Recombinant Antibody (clone JB11-40) | WB, IHC, FC | Rabbit IgG |
| VS3-FY431 | Recombinant Rabbit Anti-CXCR5 Antibody (clone R03-8K7) | WB | Rabbit IgG |
| VS-0723-WK68 | Human Anti-CXCR5 Recombinant Antibody (VS-0723-WK68) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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