Anti-Human CXCR5 Recombinant Antibody (h2C9) (CAT#: TAB-163MZ)
This antibody that specifically binds to human CXCR5 may be used for the treatment of rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, and other B-cell-dependent autoimmune diseases.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 1 shows a representative experiment of the concentration dependent binding of purified murine anti-CXCR5 antibody 2C9 to CHOal6 cells expressing human CXCR5 in cell ELISA.
FC
Figure 2 shows the binding of the humanized antibodies.
Daudi target cells were incubated with the antibodies and binding was detected using a fluorescently labeled secondary antibody and subsequent analysis via flow cytometry (FACS)
Inhib
Figure 3 shows the inhibition of CXCL13 (50 nM) induced Ca- mobilization by humanized, glycoengineered anti-CXCR5 antibody
FuncS
Figure 4 shows the depleting activity of different humanized, glycoengineered antibodies.
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- h2C9
- Applications
- ELISA, FC, FuncS, Inhib
- Related Disease
- Rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, and other B-cell-dependent autoimmune diseases
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry, Functional Assay, Inhibition.
Target
- Alternative Names
- CXCR5; chemokine (C-X-C motif) receptor 5; BLR1; CD185; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
- Gene ID
- 643
- UniProt ID
- A0N0R2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1702z | Mouse Anti-CXCR5 Recombinant Antibody (clone 28C11) | FC, ICC, IHC, Neut | Mouse IgG2b |
| MOB-2070MZ | Recombinant Mouse Anti-Human CXCR5 Antibody (clone 62606.222) | FC | Mouse antibody |
| HPAB-0114-LSX | Human Anti-CXCR5 Recombinant Antibody (clone 40C01-VH1-Vk3) | FC, Inhib | Human IgG |
| HPAB-0115-LSX | Human Anti-CXCR5 Recombinant Antibody (clone 40C01-VH2-Vk3) | FC, Inhib | Human IgG |
| VS3-FY431 | Recombinant Rabbit Anti-CXCR5 Antibody (clone R03-8K7) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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