Anti-Mouse Cdh5 Recombinant Antibody (E4B9) (CAT#: TAB-283CQ)
The antibody specifically binds to domain 1 of an extracellular domain of a VE-cadherin peptide and inhibits new junction formation without disrupting existing junctions.
Specific Inquiry
FuncS
Figure 1 Antibody E4B9 does not exhibit significant effect on paracellular permeability. Antibodies E4B9 and 6D10 do not exert dramatic effect on vascular permeability.
FuncS
Figure 2 Antibody E4B9 exhibits potent anti-angiogenesis activity in mouse corneal micropocket assay.
Three representative eyes from each experimental group (6 mice/group) are tested. Antibody E4B9 possesses>80% inhibitory activity on corneal neovascularization.
FuncS
Figure 3 Effects of the anti-ECD1 (extracellular domain) peptides antibodies on paracellular permeability of H5V cells.
Specifications
- Immunogen
- N-terminal domain 1 of mouse VE-cadherin
- Host Species
- Rat
- Specificity
- Mouse
- Species Reactivity
- Mouse, Human
- Clone
- E4B9
- Applications
- FuncS
- Related Disease
- Lung cancer
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
- Alternative Names
- Cdh5; Cadherin 5; VE-cadherin; 7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225
- Gene ID
- 12562
- UniProt ID
- P55284
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-283CQ-S(P) | Anti-Mouse Cdh5 Recombinant Antibody scFv Fragment (E4B9) | ELISA, WB, IF | |
| TAB-283CQ-F(E) | Anti-Mouse Cdh5 Recombinant Antibody Fab Fragment (E4B9) | ELISA, WB, IF |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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