Rat Anti-Clec4e Recombinant Antibody (NEUT-470CQ) (CAT#: NEUT-470CQ)
This antibody is a rat monoclonal antibody that binds specifically to mMincle, and it can neutralize the bioactivity of mMincle.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/if_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/13398_B_7_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/13398_B_7_5.jpg
Figure 3 Cerebellum
(Cells in granular layer Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/13398_B_7_8.jpg
(Cells in granular layer Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Cells in molecular layer Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Purkinje cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/13398_B_7_8.jpg
Figure 4 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/13398_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4935/13398_A_7_5.jpg
Figure 5 RNA cell line category: Group enriched (NB-4, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166523-CLEC4E
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166523-CLEC4E
Specifications
- Host Species
- Rat
- Type
- Rat IgG2b
- Specificity
- Mouse Clec4e
- Species Reactivity
- Mouse
- Applications
- Neut, FC
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Clec4e; C-type lectin domain family 4, member e; C86253; Mincle; Clecsf9
- Gene ID
- 56619
- UniProt ID
- Q9R0Q8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CLEC4E"
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IgG Antibody Products
Neutralizing Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3220z | Mouse Anti-CLEC4E Recombinant Antibody (clone 27D8) | WB, ICC, IF, IHC, FC, ELISA | Mouse IgG2b |
| MOB-1110MZ | Recombinant Mouse Anti-Human CLEC4E Antibody (clone BU27F4) | ELISA, IHC-P WB | Mouse antibody |
| FN-114CQ | Rat Anti-Clec4e Recombinant Antibody (FN-114CQ) | FuncS | Rat IgG1, κ |
| FN-116CQ | Rat Anti-CLEC4E Recombinant Antibody (FN-116CQ) | FC | Rat IgG2b, κ |
| FN-118CQ | Mouse Anti-CLEC4E Recombinant Antibody (FN-118CQ) | FuncS | Mouse IgG1, κ |
Customer Reviews and Q&As
Customer Review
Q&As
Excellent Flow Cytometry Compatibility
I've included this antibody in my flow cytometry protocol, and it's been effective. The antibody binds selectively to Clec4e, allowing for accurate cell population characterisation.
Superior Sensitivity
The sensitivity of the Rat Anti-Clec4e Recombinant Antibody (clone 6G5) is noteworthy. I was able to detect low quantities of Clec4e in my samples, which is critical when investigating proteins with low expression.
Ideal for Detailed Studies
This antibody is appropriate for research that require a close look at Clec4e expression levels. Its performance in a wide range of assays has tremendously aided my research efforts.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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