Afuco™ Anti-Human DCHS1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-196CL)
Anti-DCHS1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a human antibody capable of binding to human CDH19 on the surface of a target cell, it can be used for the treatment or amelioration of a melanoma disease or metastatic melanoma disease.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HUVEC TERT2
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/1752_B1_18_cr5804bf34eb55b_selected.jpg
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/1752_B1_18_cr5804bf34eb55b_selected.jpg
Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/ihc_selected.jpg
(Immunohistochemical staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/ihc_selected.jpg
Figure 3 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_6_3_selected.jpg
(Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_6_3_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_B_9_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_9_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_7_5.jpg
Figure 7 Endometrium
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/109028_B_4_3.jpg
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/109028_B_4_3.jpg
Figure 8 RNA cell line category: Cell line enhanced (AF22, HUVEC TERT2, REH, SH-SY5Y, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166341-DCHS1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166341-DCHS1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Melanoma
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- DCHS1; dachsous cadherin-related 1; FIB1; CDH19; CDH25; CDHR6; PCDH16; VMLDS1; Cadherin-19; Cadherin 19; Protein dachsous homolog 1; protocadherin-16; protocadherin 16; cadherin-25; cadherin 25; fibroblast cadherin-1; fibroblast cadherin
- Gene ID
- 8642
- UniProt ID
- Q96JQ0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1429CL-S(P) | Anti-Human DCHS1 Recombinant Antibody scFv Fragment | ELISA, WB | Fully human antibody |
| TAB-1429CL-F(E) | Anti-Human DCHS1 Recombinant Antibody Fab Fragment | ELISA, WB | Fully human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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