Afuco™ Anti-Human DCHS1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-196CL)
Anti-DCHS1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. This is a human antibody capable of binding to human CDH19 on the surface of a target cell, it can be used for the treatment or amelioration of a melanoma disease or metastatic melanoma disease.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HUVEC TERT2
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/1752_B1_18_cr5804bf34eb55b_selected.jpg
(Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/1752_B1_18_cr5804bf34eb55b_selected.jpg
Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/ihc_selected.jpg
(Immunohistochemical staining of human esophagus shows strong cytoplasmic and nucleolar positivity in squamous epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/ihc_selected.jpg
Figure 3 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_6_3_selected.jpg
(Immunohistochemical staining of human rectum shows strong cytoplasmic positivity in granular pattern in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_6_3_selected.jpg
Figure 4 Cerebral cortex
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_B_9_5.jpg
(Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_B_9_5.jpg
Figure 5 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_9_4.jpg
Figure 6 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_7_5.jpg
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/50246/112393_A_7_5.jpg
Figure 7 Endometrium
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/109028_B_4_3.jpg
(Cells in endometrial stroma Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17970/109028_B_4_3.jpg
Figure 8 RNA cell line category: Cell line enhanced (AF22, HUVEC TERT2, REH, SH-SY5Y, TIME)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166341-DCHS1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166341-DCHS1
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Melanoma
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- ≤6 months at 4°C; ≥6 months at -20°C.
Target
- Alternative Names
- DCHS1; dachsous cadherin-related 1; FIB1; CDH19; CDH25; CDHR6; PCDH16; VMLDS1; Cadherin-19; Cadherin 19; Protein dachsous homolog 1; protocadherin-16; protocadherin 16; cadherin-25; cadherin 25; fibroblast cadherin-1; fibroblast cadherin
- Gene ID
- 8642
- UniProt ID
- Q96JQ0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Human Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1429CL-S(P) | Anti-Human DCHS1 Recombinant Antibody scFv Fragment | ELISA, WB | Fully human antibody |
| TAB-1429CL-F(E) | Anti-Human DCHS1 Recombinant Antibody Fab Fragment | ELISA, WB | Fully human antibody |
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For Research Use Only. Not For Clinical Use.
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