Anti-Human DDR1 Recombinant Antibody (DDR1-ab2) (CAT#: TAB-177MZ)
This antibody has been found to exhibit high affinity and specificity for human DDR1, which is able to internalize DDR1 into cells quickly and kill cancer cells when conjugated to a drug such as a toxin.
Specific Inquiry
FuncS
Figure 1 shows the results of cell proliferation assays for the indicated cells treated with DDR1- ab2 and a secondary antibody to human IgG carrying saporin.
FuncS
Figure 2 shows the results of cell proliferation assays for the indicated cells (AN3CA) treated with DDRl-ab2 (white triangle) or DDRl-ab2 plus a secondary antibody to human IgG carrying saporin (·).
FuncS
Figure 3 shows the results obtained in an in vivo tumor model in mice with DDRl-ab2-tox.
FuncS
Figure 4 shows the results obtained with DDRl-ab2-tox an in vivo model of AN3CA human endometrial tumor in mice.
Specifications
- Host Species
- Human
- Derivation
- Phagemid antibody library
- Type
- Human antibody
- Specificity
- Human
- Clone
- DDR1-ab2
- Applications
- FuncS
- Related Disease
- Cancer, tumorous disease
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay.
Target
- Alternative Names
- DDR1; discoidin domain receptor tyrosine kinase 1; CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; CD167; EDDR1; MCK10; NTRK4; PTK3A; epithelial discoidin domain-containing receptor 1; tyrosine kinase DDR; cell adhesion kinase; mammary carcinoma kinase 10; tyrosine-protein kinase CAK; protein-tyrosine kinase RTK-6; neuroepithelial tyrosine kinase; PTK3A protein tyrosine kinase 3A; CD167 antigen-like family member A; neurotrophic tyrosine kinase, receptor, type 4
- Gene ID
- 780
- UniProt ID
- Q08345
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-176MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab1) | FuncS | Human antibody |
| TAB-178MZ | Anti-Human DDR1 Recombinant Antibody (DDR1-ab3) | FuncS | Human antibody |
| TAB-176MZ-S(P) | Anti-Human DDR1 Recombinant Antibody scFv Fragment (DDR1-ab1) | IF | Human antibody |
| TAB-177MZ-S(P) | Anti-Human DDR1 Recombinant Antibody scFv Fragment (DDR1-ab2) | IF | Human antibody |
| PABX-043-S (P) | Recombinant Mouse Anti-DDR1 Antibody scFv Fragment (3E3) | WB, Neut, FuncS | scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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