Recombinant Human Anti-DENV-1 Antibody (PABL-443) (CAT#: PABL-443)
Recombinant Human Antibody is capable of binding to DENV-1, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-DENV-1 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-DENV-1 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. HMAb 1F4, a DENV1-specific Abs, can neutralize DENV at different stages of viral entry in a cell type and receptor dependent manner. HMAb 1F4 binds to the DI and DI-II hinge regions of the E protein monomer and that Ab binding is likely to be sensitive to the hinge angle between DI-II.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Recombinant human anti-DENV E protein Antibody (PABL-443) in SDS-PAGE
Lane M: Marker
Lane 1: PABL-443 in non-reduced condition.
Lane 2: PABL-443 in reduced condition.
HPLC
Figure 2 Recombinant human anti-DENV E protein Antibody (PABL-443) in HPLC
HPLC analysis of PABL-443 shows the purity is>95%.
Specifications
- Immunogen
- Dengue virus 1
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native DENV-1
- Species Reactivity
- DENV
- Applications
- ELISA 1:1000-1:20000
FC Assay-depended
Neut Assay-depended
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- Assay-depended
Target
- Alternative Names
- Dengue virus; DENV; Flaviviridae; dengue virus 1; DENV 1; Flaviviridae
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
ScFv Antibody Products
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Epitope-Specific Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-440 | Recombinant Human Anti-DENV-1 Antibody Fab Fragment (HMAb 1F4 ) | ELISA, FACS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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