Recombinant Mouse Antibody (14G7) is capable of binding to EBOV GP, expressed in Chinese Hamster Ovary cells (CHO). Antibody 14G7 is protective against lethal Ebola virus challenge and recognizes a distinct linear epitope in the prominent mucin-like domain of the Ebola virus glycoprotein GP.
Figure 1 VSR-marked organelle colocalized with AtPep12p-marked compartments in pea and tomato cells.
Anti-VSR monoclonal antibodies (14G7 and 17F9) were compared to either anti-AtPep12p (AtSYP21) or anti-AtELP polyclonal antibodies via double labeling of confocal immunofluorescence in root-tip cells derived from pea (panels 1, 2, 4) and tomato (panels 3 and 4). The open arrows and arrowheads indicate examples of colocalization and separation of the two antibodies, respectively. n, nucleus. Bar = 10 mm.
Li, Y. B., Rogers, S. W., Tse, Y. C., Lo, S. W., Sun, S. S., Jauh, G. Y., & Jiang, L. (2002). BP-80 and homologs are concentrated on post-Golgi, probable lytic prevacuolar compartments. Plant and Cell Physiology, 43(7), 726-742.
Figure 2 Anti-BP-80 antibodies recognize the Arabidopsis BP-80 homolog VSR At-1.
The truncated form (missing its TMD/CT) of VSR At-1 , which is identical to AtELP, was expressed and secreted in insect cells. For Western blot detection, affinity-purified recombinant protein equivalent to 100 ml of culture media was loaded on to each lane, followed by SDS-PAGE and immunoblotting. Each identical strip was labeled by individual anti-BP-80 antibodies. The arrow indicates the position of the truncated AtBP-80. The individual antibody used in Western blot detection is indicated above each lane (1-5). The positions of molecular mass marker are indicated in kilodaltons on the left.
Li, Y. B., Rogers, S. W., Tse, Y. C., Lo, S. W., Sun, S. S., Jauh, G. Y., & Jiang, L. (2002). BP-80 and homologs are concentrated on post-Golgi, probable lytic prevacuolar compartments. Plant and Cell Physiology, 43(7), 726-742.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-298-F(E) | Recombinant Anti-EBOV GP Antibody Fab Fragment | RIA, ELISA, FuncS | Fab |
HPAB-592-FY-F(E) | Mouse Anti-EBOV GP Recombinant Antibody; Fab Fragment (HPAB-592-FY-F(E)) | WB, ELISA, Neut | Mouse Fab |
HPAB-0734YY-F(E) | Human Anti-EBOV GP Recombinant Antibody; Fab Fragment (HPAB-0734YY-F(E)) | ELISA, Neut | Human Fab |
HPAB-0735YY-F(E) | Human Anti-EBOV GP Recombinant Antibody; Fab Fragment (HPAB-0735YY-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-0736YY-F(E) | Human Anti-EBOV GP Recombinant Antibody; Fab Fragment (HPAB-0736YY-F(E)) | ELISA, Neut | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABL-458 | Recombinant Human Anti-EBOV GP Antibody (KZ52 ) | Neut | IgG |
HPAB-592-FY | Mouse Anti-EBOV GP Recombinant Antibody (HPAB-592-FY) | ELISA, Neut, Inhib, SPR, ADCC, WB | Mouse IgG |
HPAB-1098WJ | Mouse Anti-EBOV GP Recombinant Antibody (HPAB-1098WJ) | ELISA, WB | Mouse IgG, κ |
HPAB-0734YY | Human Anti-EBOV GP Recombinant Antibody (HPAB-0734YY) | ELISA, Neut | Human IgG1 |
HPAB-0735YY | Human Anti-EBOV GP Recombinant Antibody (HPAB-0735YY) | ELISA, Neut | Humanized IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBW-038 | Recombinant Mouse Anti-EBOV GP Antibody scFv Fragment (14G7) | ELISA, Neut | scFv |
PABJ-0009-S(P) | Human Anti-EBOV GP Recombinant Antibody (clone EBOV-520); scFv Fragment | ELISA, Neut | Human scFv |
FAMAB-0154WJ-S(P) | Human Anti-EBOV GP Recombinant Antibody (clone 2G1); scFv Fragment | ELISA, WB, Neut | Human scFv |
PSBS-0002 | Human Anti-Ebola virus glycoprotein Recombinant Antibody (Clone 100); scFv Fragment | ELISA, Neut, FuncS | Human scFv |
PABJ-0144-S(P) | Human Anti-EBOV GP Recombinant Antibody (clone 3T0331); scFv Fragment | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-927LC | Mouse Anti-EBOV GP Recombinant Antibody (MRO-927LC) | ELISA | Mouse IgG1, κ |
MRO-927LC-S(P) | Mouse Anti-EBOV GP Recombinant Antibody (MRO-927LC-S(P)); scFv Fragment | ELISA | Mouse scFv |
MRO-927LC-F(E) | Mouse Anti-EBOV GP Recombinant Antibody (MRO-927LC-F(E)); Fab Fragment | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-936LC | Human Anti-EBOV GP Recombinant Antibody (MRO-936LC) | ELISA | Human IgG1, κ |
MRO-917LC-S(P) | Anti-EBOV GP Recombinant Antibody scFv Fragment (EVB100) | ELISA | Human antibody |
MRO-918LC-S(P) | Anti-EBOV GP Recombinant Antibody scFv Fragment (EVB166) | ELISA | Human antibody |
MRO-919LC-S(P) | Anti-EBOV GP Recombinant Antibody scFv Fragment (EVB167) | ELISA | Human antibody |
MRO-920LC-S(P) | Anti-EBOV GP Recombinant Antibody scFv Fragment (EVB165) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-937LC | Anti-EBOV GP Recombinant Antibody (CAN9G1) | ELISA, WB | Mouse antibody |
MRO-938LC | Anti-EBOV GP Recombinant Antibody (CAN8G1) | ELISA, WB | Mouse antibody |
MRO-939LC | Anti-EBOV GP Recombinant Antibody (CAN7G1) | ELISA, WB | Mouse antibody |
MRO-900LC-S(P) | Anti-EBOV GP Recombinant Antibody scFv Fragment (13F6) | ELISA | Mouse antibody |
MRO-901LC-S(P) | Anti-EBOV GP Recombinant Antibody scFv Fragment (6D8) | ELISA | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
EPAF-0983LC | Recombinant Mouse Anti-EBOV GP Antibody (133/3.16) | ELISA, FuncS | IgG1 |
EPAF-0213CQ | Recombinant Mouse Anti-EBOV GP Antibody (226/8.1) | Neut | IgG1 |
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