Afuco™ Anti-Human ECSCR ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-212CL)
Anti-ECSCR ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. They are antibodies which bind ECSCR and inhibit chemotaxis. The antibodies may bind an epitope QTVPPNSTTM on the extracellular domain of ECSCR. The antibodies, which may be provided as a pharmaceutical composition, may be used to inhibit tumour cell invasion and may be used in the treatment of diseases, for example diseases associated with angiogenesis such as cancer.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63337/1769_A8_8_cr59e0801e38b23_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, plasma membrane & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63337/1769_A8_8_cr59e0801e38b23_selected.jpg
Figure 2 RNA cell line category: Group enriched (EFO-21, HUVEC TERT2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000249751-ECSCR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000249751-ECSCR
Specifications
- Host Species
- Chimeric
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- 95% by HPLC
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- ECSCR; endothelial cell surface expressed chemotaxis and apoptosis regulator; ARIA; ECSM2; apoptosis regulator through modulating IAP expression; endothelial cell-specific molecule 2
- Gene ID
- 641700
- UniProt ID
- Q19T08
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Mouse Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3014z | Recombinant Anti-Human ECSCR Antibody | ELISA, IP, FuncS | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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