Afuco™ Anti-Human EMP2 ADCC Recombinant Antibody (PG-101), ADCC Enhanced (CAT#: AFC-219CL)

Anti-EMP2 ADCC Enhanced Antibody (PG-101) is an ADCC enhanced antibody produced by our Afuco™ platform. This is a novel IgG1 monoclonal antibody to EMP2, PG-101 treatment in the primary tumor is sufficient to reduce secondary tumor formation in triple negative breast cancer cells on the order of 1:20, 000 compared to the control treated mice. PG-101 in combination with docetaxel can cure up to 80% of animals treated. This effect is lasting as these mice have shown no rebound in tumor load more than 2 months following the last treatment. Collectively, these results show that PG-101 therapy has the potential to revolutionize the outcomes for women with breast cancer.


Specific Inquiry
  • Size:
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  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Species
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Cancer

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

Target

  • Alternative Names
  • EMP2; epithelial membrane protein 2; XMP; NPHS10; EMP-2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "EMP2"

Recombinant Antibody

CAT Product Name Application Type
MOB-317 Recombinant Anti-human EMP2 Antibody WB, Neut, FuncS IgG

Fab Fragment Antibody

CAT Product Name Application Type
MOB-317-F(E) Recombinant Anti-human EMP2 Antibody Fab Fragment IP, IF, FuncS Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-317-S(P) Recombinant Anti-human EMP2 Antibody scFv Fragment ELISA, IP, FuncS scFv

Rat Antibody

CAT Product Name Application Type
TAB-231CL Human Anti-EMP2 Recombinant Antibody (TAB-231CL) ELISA Human IgG1

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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