Anti-Human ENG Recombinant Antibody (TRC105) (CAT#: TAB-232CL)

Recombinant Chimeric (human/mouse) monoclonal antibody expressed in CHO binding to Human ENG. TRC105 is a novel, clinical stage antibody to endoglin, which is a protein that is overexpressed on endothelial cells and is essential for angiogenesis, the process of new blood vessel formation. TRC105 is currently being studied in clinical trials for the treatment of multiple solid tumor types, including soft tissue sarcoma, renal cell carcinoma, glioblastoma, hepatocellular carcinoma and colorectal cancer, in combination with VEGF inhibitors.


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SDS-PAGE

Figure 1 Anti-Human ENG Recombinant Antibody (TAB-232CL) in SDS-PAGE

Figure 1 Anti-Human ENG Recombinant Antibody (TAB-232CL) in SDS-PAGE

Lane 1: 2 μg, Reducing mAb Lane M: Protein Marker


Specifications

  • Host Species
  • mouse
  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Solid Tumors

Product Property

  • Purity
  • Purity>95% by SDS-PAGE
  • Storage
  • ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C

Target

  • Alternative Names
  • ENG; endoglin; END; HHT1; ORW1; CD105 antigen

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "ENG"

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0189MZ Chicken Anti-Endoglin Polyclonal IgY WB Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-726CQ Mouse Anti-ENG Recombinant Antibody (clone 7D11) WB, Neut Mouse IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1150 Hi-Affi™ Rabbit Anti-ENG Recombinant Antibody (clone DS1150AB) WB, IHC-P, IP, FC Rabbit IgG

Chimeric Antibody

CAT Product Name Application Type
TAB-013ML Anti-Human ENG Recombinant Antibody (Carotuximab) ELISA, IHC, FC, IP, IF, Inhib IgG1, κ

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-013ML Afuco™ Anti-ENG ADCC Recombinant Antibody (Carotuximab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

Single-domain Antibody

CAT Product Name Application Type
HPAB-0707-YJ-VHH Camelid Anti-ENG Recombinant Single Domain Antibody (AR1-86) ELISA, ICC Camelid VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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