Anti-Human EPCAM Recombinant Antibody (h12H8C) (CAT#: TAB-375MZ)
This antibody h12H8C specifically binds to epithelial cell adhesion/activating molecule EpCAM expressed on cancer cells, which can induce cancer cell apoptosis. The antibody can be potentially used as diagnostic and therapeutic agents.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FuncS
Figure 1 shows effect of AbGn bsAbs on cytotoxic activity (% of cell death) in pancreatic cancer cell in the presence of human PBMC.
Inhib
Figure 2 shows effect of bsAbs on % of cell growth inhibition in pancreatic cancer cell in the presence of hPBMC.
FuncS
Figure 3 shows effect of AbGn bsAbs on cytotoxic activity (% of cell death) in Multiple Myeloma cell RPMI 8266 in the presence of human PBMC.
Inhib
Figure 4 shows effect of bsAbs on % of cell growth inhibition in lung cancer cell NCI-H358 in the presence of hPBMC.
FuncS
Figure 5 shows antitumor activity of hl2H8CXanti-CD3 (hl2H8C-v2.1 and hl2H8C-v2.1-sHSA) in human DLD-1 colon carcinoma xenograft model (Mean+SEM) (* p<0.05 as compared to PBS control group).
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- h12H8C
- Applications
- FuncS, Inhib
- Related Disease
- Cancers such as breast cancer, colorectal cancer, gastric cancer, lung cancer, and prostate cancer
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay, Inhibition.
Target
- Alternative Names
- EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)
- Gene ID
- 4072
- UniProt ID
- P16422
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone h12H8C"
See other products for "EPCAM"
Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products
Immunotoxin Products
Human Antibody Products
Mouse Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
IgM Antibody Products
ADCC Enhanced Antibody Products
Fab Antibody Products
ScFv Antibody Products
MHC Tetramer Products for Cancer
Antibody Magnetic Beads
Cancer Stem Cell Biomarker Specific Antibody Products
ScFv-Fc Chimera Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-213 | Humanized Anti-EPCAM Recombinant Antibody (clone Tucotuzumab) | WB, Neut, ELISA, IF, IP, FuncS, FC | Humanized (from mouse) IgG1 |
| TAB-235CL | Human Anti-Human EPCAM Recombinant Antibody (3622W94) | Cyt, FC | Antibody |
| TAB-374MZ | Anti-Human EPCAM Recombinant Antibody (h12H8B) | FC, ELISA | Humanized antibody |
| TAB-376MZ | Anti-Human EPCAM Recombinant Antibody (h2D11B) | Cyt, Inhib | Humanized antibody |
| TAB-362MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) | Confocal, ELISA | Humanized antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-375MZ. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, WB, BLI, SPR
Application: FuncS, Inhib, IP, ELISA
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: Neut, FC
Application: ELISA, IHC, FC, IP, IF, FuncS
-3.jpg)
Application: Neut
Application: IF, IP, Neut, FuncS, ELISA, FC
Application: ELISA, Activ, Block
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
