Human Anti-EPHA2 Recombinant Antibody (clone 2E7); Fab Fragment (CAT#: HPAB-0338-YC-F(E))
The antibodies provided have increased affinities that preferentially bind an EphA2 epitope exposed on cancer cells but not non-cancer cells.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, PC-3, U-251 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
Specifications
- Host Species
- Human
- Derivation
- Combinatorial antibody library
- Type
- Human Fab
- Specificity
- Human EPHA2
- Species Reactivity
- Human
- Clone
- 2E7
- Applications
- ELISA
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- EPH Receptor A2; Tyrosine-Protein Kinase Receptor ECK; EC 2.7.10.1; ECK; Epithelial Cell Receptor Protein Tyrosine Kinase; Soluble EPHA2 Variant 1; Epithelial Cell Kinase; EC 2.7.10; CTRCT6; ARCC2; CTPP1; EphA2; CTPA
- Gene ID
- 1969
- UniProt ID
- P29317
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 2E7"
See other products for "EPHA2"
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-381MZ | Anti-Human EPHA2 Recombinant Antibody (LUCA40) | FC | |
| TAB-382MZ | Anti-Human EPHA2 Recombinant Antibody (SPL1) | IHC, WB, sELISA | |
| TAB-383MZ | Anti-Human EPHA2 Recombinant Antibody (SG5 ) | IHC, WB, sELISA | |
| TAB-384MZ | Mouse Anti-EPHA2 Recombinant Antibody (TAB-384MZ) | ELISA | Mouse IgG |
| TAB-380MZ-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-380MZ-S(P)) | IHC, WB, sELISA | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-385MZ | Human Anti-EPHA2 Recombinant Antibody (TAB-385MZ) | ELISA | Humanized IgG |
| TAB-385MZ-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (TAB-385MZ-S(P)) | ELISA | Humanized scFv |
| TAB-385MZ-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (TAB-385MZ-F(E)) | ELISA | Humanized Fab |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC145 | PE-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM | |
| MHC-LC146 | APC-A*02:01/Human EphA2 (TLADFDPRV) MHC Tetramer | FCM | |
| MHC-YF418 | A*02:01/Human EPHA2 (VLAGVGFFI) MHC Pentamer | FCM |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1164 | Hi-Affi™ Rabbit Anti-EPHA2 Recombinant Antibody (clone DS1164AB) | WB | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0336-YC-S(P) | Mouse Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0336-YC-S(P)) | ELISA, FC, FuncS | Mouse scFv |
| HPAB-0337-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody; scFv Fragment (HPAB-0337-YC-S(P)) | ELISA, FC, FuncS | Humanized scFv |
| HPAB-0338-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody (clone 2E7); scFv Fragment | ELISA | Human scFv |
| HPAB-0339-YC-S(P) | Mouse Anti-EPHA2 Recombinant Antibody (clone EA5); scFv Fragment | ELISA, FC, FuncS | Mouse scFv |
| HPAB-M0068-YC-S(P) | Human Anti-EPHA2 Recombinant Antibody (clone D2-1A7); scFv Fragment | Inhib | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0450-CN-F(E) | Mouse Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0450-CN-F(E)) | ELISA, WB, FC, IP | Mouse Fab |
| HPAB-0452-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody; Fab Fragment (HPAB-0452-CN-F(E)) | ELISA, WB, FC, IP | Humanized Fab |
| HPAB-0453-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone 4H5); Fab Fragment | ELISA, FC, IF | Humanized Fab |
| HPAB-0454-CN-F(E) | Human Anti-EPHA2 Recombinant Antibody (clone 2A4); Fab Fragment | ELISA, FC, IF, Agonist | Humanized Fab |
| HPAB-0455-CN-F(E) | Mouse Anti-EPHA2 Recombinant Antibody (clone EA2); Fab Fragment | ELISA, FC, IF | Mouse Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0164CQ | Human Anti-EPHA2 Recombinant Antibody (clone G5) | ELISA, IF, FC, FuncS, Inter | Humanized IgG1 |
| HPAB-0165CQ | Mouse Anti-EPHA2 Recombinant Antibody (clone B233) | ELISA, IF, FC, FuncS | Mouse IgG |
| HPAB-0166CQ | Mouse Anti-EPHA2 Recombinant Antibody (clone B208) | ELISA, IF, FC, FuncS | Mouse IgG |
| HPAB-0167CQ | Human Anti-EPHA2 Recombinant Antibody (clone 3F2) | ELISA, IF, FC, FuncS | Human IgG |
| HPAB-0168CQ | Human Anti-EPHA2 Recombinant Antibody (clone 1F12) | ELISA, IF, FC, FuncS, Activ | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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