Mouse Anti-EPHA2 Recombinant Antibody (clone EA2); Fab Fragment (CAT#: HPAB-0455-CN-F(E))
EA2 is an EphA2 agonistic antibody that binds to and agonizes EphA2, thereby increasing EphA2 phosphorylation and decreasing EphA2 levels in cells which EphA2 has been agonized. EA2 selectively binds to malignant cells and is immunoreactive against malignant prostate cells.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to nuclear speckles, plasma membrane, the Golgi apparatus & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10464/991_D3_3_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (CAPAN-2, PC-3, U-251 MG, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142627-EPHA2
Specifications
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human EPHA2
- Species Reactivity
- Human
- Clone
- EA2
- Applications
- ELISA, FC, IF
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- EPH Receptor A2; Tyrosine-Protein Kinase Receptor ECK; EC 2.7.10.1; ECK; Epithelial Cell Receptor Protein Tyrosine Kinase; Soluble EPHA2 Variant 1; Epithelial Cell Kinase; EC 2.7.10; CTRCT6; ARCC2; CTPP1; EphA2; CTPA
- Gene ID
- 1969
- UniProt ID
- P29317
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-083 | Human Anti-EPHA2 Recombinant Antibody (clone 1C1) | ELISA, WB, FuncS | Human IgG |
| HPAB-0450-CN | Mouse Anti-EPHA2 Recombinant Antibody (HPAB-0450-CN) | ELISA, WB, FC, IP | Mouse IgG2a |
| HPAB-0452-CN | Human Anti-EPHA2 Recombinant Antibody (HPAB-0452-CN) | ELISA, WB, FC, IP | Humanized IgG1 |
| HPAB-0453-CN | Human Anti-EPHA2 Recombinant Antibody (clone 4H5) | ELISA, FC, IF | Humanized IgG |
| HPAB-0454-CN | Human Anti-EPHA2 Recombinant Antibody (clone 2A4) | ELISA, FC, IF, Agonist | Humanized IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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