Recombinant Llama Anti-ERBB3 Single Domain Antibody (BCD090-M2) (CAT#: PABC-556)

This product is a recombinant Llama antibody that can recognize ErbB3. BCD090-M2 recognises erbB3, a receptor tyrosine kinase.

  • Published Data
  • Datasheet
  • MSDS
  • COA
SPR

Figure 1 Binding of BCD090-M2 VHH antibody to the extracellular domain of human ErbB3 receptor analyzed by surface plasmon resonance.

Eliseev, I. E., Yudenko, A. N., Vysochinskaya, V. V., Svirina, A. A., Evstratyeva, A. V., Drozhzhachih, M. S., ... & Ulitin, A. B. (2018). Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Research, 7.

SPR

Figure 2 Binding of BCD090-M2 VHH antibody to the extracellular domain of human ErbB3 receptor analyzed by surface plasmon resonance.

Fitting of the measured response as a function of concentration of free BCD090-M2 in solution with a simple bimolecular equilibrium binding model gives KD=1 μM.

Eliseev, I. E., Yudenko, A. N., Vysochinskaya, V. V., Svirina, A. A., Evstratyeva, A. V., Drozhzhachih, M. S., ... & Ulitin, A. B. (2018). Crystal structures of a llama VHH antibody BCD090-M2 targeting human ErbB3 receptor. F1000Research, 7.


Specifications

  • Host Species
  • Llama
  • Type
  • Llama VHH
  • Specificity
  • Human ErbB3
  • Species Reactivity
  • Human
  • Clone
  • BCD090-M2
  • Applications
  • ELISA, SPR

Applications

  • Application Notes
  • This antibody has been reported for use in Surface Plasmon Resonance and Enzyme-linked Immunosorbent Assay. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • Erb-B2 Receptor Tyrosine Kinase 3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; Tyrosine Kinase-Type Cell Surface Receptor HER3; Human Epidermal Growth Factor Receptor 3; Proto-Oncogene-Like Protein C-ErbB-3; EC 2.7.10.1; HER3; Lethal Congenital Contracture Syndrome 2; P180-ErbB3; P45-SErbB3; P85-SErbB3; EC 2.7.10; MDA-BF-1; C-ErbB-3; C-ErbB3; ErbB3-S; ErbB-3; LCCS2

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

See other products for "ERBB3"

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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