Mouse Anti-ESR1 Recombinant Antibody (clone 33) (CAT#: NEUT-750CQ)
This antibody is a mouse monoclonal antibody that binds specifically to Estrogen Receptor alpha, and it can neutralize the bioactivity of Estrogen Receptor alpha.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1134_D1_1_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1134_D1_1_selected.jpg
Figure 2 IF staining of human cell line RT4
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1423_D4_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1423_D4_1_blue_red_green.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1_G2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/449/1_G2_1_blue_red_green.jpg
Figure 4 Endometrium
(Cells in endometrial stroma
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37/288_B_3_3.jpg
(Cells in endometrial stroma
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/37/288_B_3_3.jpg
Figure 5 RNA cell line category: Group enriched (MCF7, T-47d)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091831-ESR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091831-ESR1
Specifications
- Immunogen
- Synthetic peptide corresponding to the residues E(247) V G M M K G G I R K D R R G(261) of the ER alpha DNA binding domain.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human ESR1
- Species Reactivity
- Human, Mouse, Rat, Fish, Primate, Sheep, Bovine, Avian
- Clone
- 33
- Applications
- Block, FC, GS, ELISA, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ESR1; estrogen receptor 1; ER; ESR; Era; ESRA; ESTRR; NR3A1
- Gene ID
- 2099
- UniProt ID
- P03372
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "ESR1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-898-VHH | Recombinant Anti-Human ESR1 VHH Single Domain Antibody | FA, FC, ICC, ELISA | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0305MZ | Recombinant Mouse Anti-Human Estrogen Receptor α Antibody (clone 2E6) | IHC | Mouse antibody |
| ZG-0742F | Mouse Anti-ESR1 Recombinant Antibody (clone AER311) | WB, IP, IHC, ELISA, WB | Mouse IgG2a |
| ZG-0743F | Mouse Anti-ESR1 Recombinant Antibody (clone AER314) | IP, ELISA, IHC, WB | Mouse IgG1 |
| VS3-QX386 | Mouse Anti-ESR1 Recombinant Antibody (clone 6F11-C3-G6) | WB | Mouse IgG2b |
| VS3-QX387 | Mouse Anti-ESR1 Recombinant Antibody (clone 415CT16.3.2.1) | WB | Mouse IgG1 |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0197MZ | Chicken Anti-ESR1 Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-751CQ | Mouse Anti-ESR1 Recombinant Antibody (clone TE111.5D11) | FC, IP, WB, Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1201 | Hi-Affi™ Rabbit Anti-ESR1 Recombinant Antibody (clone DS1201AB) | IHC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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