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    Anti-Mouse Emb Recombinant Antibody (2G21) (CAT#: TAB-328MZ)

    This antibody 2G21 showing cytotoxicity or a cytotoxicity inducing activity provides a potentially agent for the prophylaxis or therapy of autoimmune diseases or allergic diseases.

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    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FC

    Figure 1 is a figure shows evaluation of a binding activity of an anti-Embigin antibody to mouse Embigin expressing rat cells and rat cells by flow cytometry.

    Figure 1 is a figure shows evaluation of a binding activity of an anti-Embigin antibody to mouse Embigin expressing rat cells and rat cells by flow cytometry.

    Isotype (rat IgG) relative to the anti-Embigin antibody was 5 μg/mL concentration, and a culture supernatant was used as the anti-Embigin antibody (anti-emb antibody).

    FuncS

    Figure 2 is a figure shows evaluation of cell depletion specificity of a toxin-modified anti-Embigin antibody in pathogenic cells.

    Figure 2 is a figure shows evaluation of cell depletion specificity of a toxin-modified anti-Embigin antibody in pathogenic cells.

    FuncS

    Figure 3 is a figure shows evaluation of the clinical score of a multiple sclerosis model by transferring cells after selectively depleting Th17 cells with an anti-Embigin antibody into a mouse.

    Figure 3 is a figure shows evaluation of the clinical score of a multiple sclerosis model by transferring cells after selectively depleting Th17 cells with an anti-Embigin antibody into a mouse.

    FuncS

    Figure 4 is a figure shows evaluation of an efficacy, on clinical score, of administration of, before onset of pathology, an anti-Embigin antibody to a mouse induced to make a multiple sclerosis model by immunizing with PLP.

    Figure 4 is a figure shows evaluation of an efficacy, on clinical score, of administration of, before onset of pathology, an anti-Embigin antibody to a mouse induced to make a multiple sclerosis model by immunizing with PLP.

    PLP was mixed with Freund's complete adjuvant and subcutaneously immunized once. The anti-Embigin antibody (300 μg) was administered twice on days 7 and 14 (shown by arrows) after immunization. The clinical score was evaluated until day 18 after PLP immunization.


    Specifications

    • Immunogen
    • Mouse Embigin overexpressing cells
    • Host Species
    • Rat
    • Specificity
    • Mouse
    • Clone
    • 2G21
    • Applications
    • FC, FuncS
    • Related Disease
    • Multiple sclerosis, psoriasis, rheumatism, chronic noninfectious uveitis, and glomerulonephritis

    Applications

    • Application Notes
    • This antibody has been reported for use in Flow Cytotoxicityometry, Functional Assay.

    Target

    • Alternative Names
    • Gp70; AL022799

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    NAB-850-VHH Recombinant Anti-Human EMB VHH Single Domain Antibody ICC, ChiP, FC, FA Llama VHH

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