Human Anti-F Recombinant Antibody (PABC-139) (CAT#: PABC-139)
Recombinant human antibody is capable of binding to HMPV F, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HMPV F mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-HMPV F proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody DS7, which is a potently neutralizing anti-human metapneumovirus antibody, binds a structurally invariant domain of F, revealing a new epitope that could be targeted in vaccine development.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human F
- Species Reactivity
- Human
- Applications
- Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- F; Fusion glycoprotein F0
- UniProt ID
- G3KCK8
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "F"
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-694 | Recombinant Mouse Anti-RSV gp F Antibody (101F) | ELISA, Neut | IgG |
| MRO-1877-CN | Rabbit Anti-F Polyclonal Antibody (MRO-1877-CN) | WB, ELISA | Rabbit IgG |
| HPAB-0139-YJ | Mouse Anti-F Recombinant Antibody (HPAB-0139-YJ) | Neut, Inhib, WB, IP | Mouse IgG1, κ |
| HPAB-0140-YJ | Human Anti-F Recombinant Antibody (HPAB-0140-YJ) | Neut, Inhib, WB, IP | Human IgG1, κ |
| HPAB-0141-YJ | Human Anti-F Recombinant Antibody (HPAB-0141-YJ) | Neut, Inhib, WB, IP | Human IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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