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    Anti-Human JAM-A Recombinant Antibody (TAB-0606CL) (CAT#: TAB-0606CL)

    This recombinant antibody is a mouse monoclonal antibody that specifically binds to human JAM-A. A KD of 22 pM of this antibody for the human JAM-A protein was determined under indicated experimental conditions. This purified antibody product can be potentially used in the immunoassays such as IF, IHC, FC, and WB in treatment research of various cancers especially lung cancer and breast cancer.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cell junctions & microtubules.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43616/if_selected.jpg
    Figure 2 IF staining of human cell line CACO-2
    Figure 2 IF staining of human cell line CACO-2
    (Immunofluorescent staining of human cell line CACO-2 shows localization to microtubules.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43616/1026_E7_1_red_green.jpg
    Figure 3 IF staining of human cell line MCF7
    Figure 3 IF staining of human cell line MCF7
    (Immunofluorescent staining of human cell line MCF7 shows localization to microtubules.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43616/965_H10_1_red_green.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_B_8_5.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Glandular cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_A_9_3.jpg
    Figure 6 Liver
    Figure 6 Liver
    (Cholangiocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_A_8_4.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Collecting ducts
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Distal tubules
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Proximal tubules (cell body)
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_A_7_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Leydig cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_A_6_6.jpg
    Figure 9 Skin
    Figure 9 Skin
    (Epidermal cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_B_4_8.jpg
    Figure 10 Lymph node
    Figure 10 Lymph node
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/61700/138414_A_8_8.jpg
    RNA Expression
    Figure 11 RNA cell line category: Cell line enhanced (HaCaT, OE19, SuSa)
    Figure 11 RNA cell line category: Cell line enhanced (HaCaT, OE19, SuSa)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000158769-F11R

    Specifications

    • Immunogen
    • MCF-7 cell
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Clone
    • 6F4
    • Applications
    • IF, IHC, FC, WB
    • Related Disease
    • Lung cancer and breast cancer

    Applications

    • Application Notes
    • The F11R antibody has been reported in applications of Western Blot, Immunofluorescence, Immunohistochemistry, Flow Cytometry. IF:Cells were treated for 48 hr with 10 lg mL1 of either the isotype control or the Mab 6F4. JAM-A expression level on cell surface was determined by immunofluorescence staining and visualized by confocal microscopy.

    Target

    • Alternative Names
    • F11R; F11 receptor; JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1; junctional adhesion molecule A; platelet F11 receptor; platelet adhesion molecule 1; junctional adhesion molecule 1
    • Long Name
    • F11 Receptor

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    NAB-914-VHH Recombinant Anti-Human F11R VHH Single Domain Antibody ICC, FC, WB, FUNC Llama VHH

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    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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