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Mouse Anti-F3 Recombinant Antibody (clone H36.D2.B7); scFv Fragment (CAT#: HPAB-0117-YC-S(P))

The antibody can bind native human TF, either alone or present in a TF: VIIa complex, effectively preventing factor X binding to TF or that complex, and thereby reducing blood coagulation. Preferred antibodies of the invention specifically bind a conformational epitope predominant to native human TF, which epitope provides an unexpectedly strong antibody binding site.


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Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
Figure 2 IF staining of human cell line HaCaT
Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
Figure 3 IHC staining of human nasopharynx
Figure 3 IHC staining of human nasopharynx
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
Figure 5 Testis
Figure 5 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
Figure 6 Placenta
Figure 6 Placenta
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3

Specifications

  • Immunogen
  • Purified rhTF
  • Host Species
  • Mouse
  • Type
  • Mouse scFv
  • Specificity
  • Human F3
  • Species Reactivity
  • Human
  • Clone
  • H36.D2.B7
  • Applications
  • ELISA, WB
  • Related Disease
  • Inflammation, Vascular diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Humanized Antibody

CAT Product Name Application Type
TAB-258CL Human Anti-F3 Recombinant Antibody (TAB-258CL) ELISA Human IgG
TAB-276CQ-S(P) Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-276CQ-S(P)) ELISA, FC Humanized scFv
TAB-278CQ-S(P) Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-278CQ-S(P)) ELISA, FC Humanized scFv
TAB-276CQ-F(E) Human Anti-F3 Recombinant Antibody; Fab Fragment (TAB-276CQ-F(E)) ELISA, FC Humanized Fab
TAB-278CQ-F(E) Human Anti-F3 Recombinant Antibody; Fab Fragment (TAB-278CQ-F(E)) ELISA, FC Humanized Fab

Fab Fragment Antibody

CAT Product Name Application Type
PFBZ-043 Mouse Anti-F3 Recombinant Antibody (clone 5G9); Fab Fragment Block Mouse Fab
PFBW-043 Human Anti-F3 Recombinant Antibody (clone D3H44); Fab Fragment WB, IHC, IF, FuncS Humanized Fab
PFBC-450 Mouse Anti-F3 Recombinant Antibody (clone 10H10); Fab Fragment ELISA, FuncS Mouse Fab
HPAB-J0088-YC-F(E) Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-J0088-YC-F(E)) ELISA, FC, IHC, FuncS Human Fab
HPAB-J0089-YC-F(E) Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-J0089-YC-F(E)) ELISA, FC, IHC, FuncS Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBZ-043 Mouse Anti-F3 Recombinant Antibody (clone 5G9); scFv Fragment Block Mouse scFv
PSBW-043 Human Anti-F3 Recombinant Antibody (clone D3H44); scFv Fragment WB, IHC, IF, FuncS Humanized scFv
PSBL-468 Human Anti-F3 Recombinant Antibody (clone 10H10); scFv Fragment WB, IF, FuncS Human scFv
HPAB-0113-YC-S(P) Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-0113-YC-S(P)) ELISA, FC, Neut Human scFv
HPAB-1000WJ-S(P) Human Anti-F3 Recombinant Antibody (clone JT C5); scFv Fragment ELISA, Inhib Human scFv

Mouse Antibody

CAT Product Name Application Type
TAB-277CQ-S(P) Mouse Anti-F3 Recombinant Antibody; scFv Fragment (TAB-277CQ-S(P)) ELISA, FC Mouse scFv
PABX-179 Recombinant Mouse Anti-TF Antibody (D3) WB, ELISA, IF, FuncS IgG
PABX-177-S (P) Recombinant Human Anti-TF Antibody scFv Fragment (D3h44) WB, ELISA, Neut, FuncS scFv
PABX-179-S (P) Recombinant Mouse Anti-TF Antibody scFv Fragment (D3) WB, ELISA, IF, FuncS scFv
PABX-179-F (E) Recombinant Mouse Anti-TF Antibody Fab Fragment (D3) WB, ELISA, IF, FuncS Fab

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-178LC Recombinant Anti-Human F3 Antibody (Non-glycosylated) ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1226 Hi-Affi™ Rabbit Anti-F3 Recombinant Antibody (clone DS1226AB) WB, IHC-P, ICC, IF Rabbit IgG

Human Antibody

CAT Product Name Application Type
TAB-473CQ Anti-Human F3 Recombinant Antibody (Tisotumab) ELISA, IHC, FC, IP, IF, Inhib IgG1, κ

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0573CQ Mouse Anti-F3 Recombinant Antibody (clone hATR-5) ELISA, Inhib Mouse IgG4

Recombinant Antibody

CAT Product Name Application Type
PABC-450 Mouse Anti-F3 Recombinant Antibody (clone 10H10) ELISA, FuncS Mouse IgG1, κ
FN-224CQ Mouse Anti-F3 Recombinant Antibody (clone HTF-1) FC, FuncS, ICC, IF, WB Mouse IgG1, κ
HPAB-1000WJ Human Anti-F3 Recombinant Antibody (clone JT C5) ELISA, Inhib Human IgG
HPAB-J0088-YC Human Anti-F3 Recombinant Antibody (HPAB-J0088-YC) ELISA, FC, IHC, FuncS Human IgG1
HPAB-J0089-YC Human Anti-F3 Recombinant Antibody (HPAB-J0089-YC) ELISA, FC, IHC, FuncS Human IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-473CQ Afuco™ Anti-F3 ADCC Recombinant Antibody (Tisotumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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