Human Anti-F3 Recombinant Antibody (clone 10H10) (CAT#: PABL-471)
Recombinant Human Antibody (10H10) is capable of binding to F3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-F3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-F3 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Inhib
Figure 1 Cell spreading of HaCaT keratinocytes on anti-TF involves several β1 integrins.
Inhibitory mAB 10H10 was added at 25 μg/ml before plating.
Dorfleutner, A., Hintermann, E., Tarui, T., Takada, Y., & Ruf, W. (2004). Cross-talk of integrin α3β1 and tissue factor in cell migration. Molecular biology of the cell, 15(10), 4416-4425.
Specifications
- Immunogen
- Human coagulation factor III (thromboplastin, tissue factor)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human F3
- Species Reactivity
- Human
- Clone
- 10H10
- Applications
- WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Inhibition.
Target
- Alternative Names
- F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor
- Gene ID
- 2152
- UniProt ID
- P13726
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-258CL | Human Anti-F3 Recombinant Antibody (TAB-258CL) | ELISA | Human IgG |
| TAB-276CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-276CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-278CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-278CQ-S(P)) | ELISA, FC | Humanized scFv |
| PABX-180 | Recombinant Human Anti-TF Antibody (D3H44) | WB, ELISA, FuncS | IgG |
| PABX-180-F (E) | Recombinant Human Anti-TF Antibody Fab Fragment (D3H44) | WB, ELISA, FuncS | Fab |
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