Recombinant Human Antibody (10H10) is capable of binding to F3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-F3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-F3 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Figure 1 Cell spreading of HaCaT keratinocytes on anti-TF involves several β1 integrins.
Inhibitory mAB 10H10 was added at 25 μg/ml before plating.
Dorfleutner, A., Hintermann, E., Tarui, T., Takada, Y., & Ruf, W. (2004). Cross-talk of integrin α3β1 and tissue factor in cell migration. Molecular biology of the cell, 15(10), 4416-4425.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
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TAB-258CL | Human Anti-F3 Recombinant Antibody (TAB-258CL) | ELISA | Human IgG |
TAB-276CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-276CQ-S(P)) | ELISA, FC | Humanized scFv |
TAB-278CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-278CQ-S(P)) | ELISA, FC | Humanized scFv |
TAB-276CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (TAB-276CQ-F(E)) | ELISA, FC | Humanized Fab |
PABX-180-F (E) | Recombinant Human Anti-TF Antibody Fab Fragment (D3H44) | WB, ELISA, FuncS | Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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