Anti-Human FAT1 Recombinant Antibody (198.3) (CAT#: TAB-030WM)
A novel tumor targeting antibody directed against colon expressed FAT1 (clone 198.3) potentially used for intracellular negative gold nanoparticles delivery, holding significant potential to improve the treatment of cancer.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23882/52199_A_5_3_selected.jpg
(Immunohistochemical staining of human rectum shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/23882/52199_A_5_3_selected.jpg
Figure 2 Cerebral cortex
(Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1869/7555_B_8_5.jpg
(Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1869/7555_B_8_5.jpg
Figure 3 Small intestine
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1869/7834_A_6_2.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1869/7834_A_6_2.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1869/7834_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1869/7834_A_7_3.jpg
Figure 5 RNA cell line category: Cell line enhanced (fHDF/TERT166, LHCN-M2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000083857-FAT1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000083857-FAT1
Specifications
- Immunogen
- Recombinant FAT1 (rFAT1)
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 198.3
- Applications
- FC, WB, IHC
- Related Disease
- Colorectal cancer
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, Western Blot, Immunohistochemistry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- FAT; ME5; CDHF7; CDHR8; hFat1; FAT1; FAT atypical cadherin 1
- Gene ID
- 2195
- UniProt ID
- Q14517
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Mouse Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4061z | Mouse Anti-FAT1 Recombinant Antibody (clone 44H5) | WB, ELISA | Mouse IgG1, κ |
| MRO-2136-CN | Rabbit Anti-FAT1 Polyclonal Antibody (MRO-2136-CN) | WB | Rabbit IgG |
| HPAB-0124-WJ | Mouse Anti-FAT1 Recombinant Antibody (HPAB-0124-WJ) | IHC, ELISA, WB | Mouse IgG2a, κ |
| VS3-WK959 | Mouse Anti-FAT1 Recombinant Antibody (VS3-WK959) | WB | Mouse IgG |
| MOB-328YC | Rabbit Anti-FAT1 Recombinant Antibody (MOB-328YC) | ELISA, FC, IP | Rabbit IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Ideal Concentration
The ready-to-use concentration was perfect for our studies. We were spared a great deal of time and expense in not having to dilute or change.
Superb Detection
The antibody is robust and produces reliable results even after several months in storage. It is extremely recommended to aliquot in order to maintain its effectiveness.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-030WM, RRID: AB_3111764)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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