Recombinant Anti-human FGFR2 Intrabody [Tat]
CAT#: IAB-B026(T)
Recombinant anti-FGFR2 intrabody in fusion with HIV Tat works within cells to bind intracellur protein FGFR2, expressed in CHO cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm, cell junctions & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/35305/if_selected.jpg
❮
❯
Specifications
- Immunogen
- human fibroblast growth factor receptor 2
- Host Species
- mouse
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- human
- Applications
- Products can be used for: Immunocytochemistry; Neutralization; Functional studies
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- FGFR2; fibroblast growth factor receptor 2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein;
- Gene ID
- 2263
- UniProt ID
- P21802
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for IAB-B026(T). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "FGFR2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B026(A) | Recombinant Anti-human FGFR2 Intrabody [(D-Arg)9] | IF, FC, FuncS | scFv-(D-Arg)9 |
| IAB-B026(G) | Recombinant Anti-human FGFR2 Intrabody [+36 GFP] | WB, ICC, FuncS | scFv-(+36GFP) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-284CL | Anti-Human FGFR2 Recombinant Antibody (BAY 1179470) | IF, WB | Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-055WM | Anti-Human FGFR2 Recombinant Antibody (GP369/4B9) | FC | |
| TAB-056WM | Mouse Anti-FGFR2 Recombinant Antibody (TAB-056WM) | IHC, ELISA, FC, Block | Mouse IgG1 |
| TAB-058WM | Rat Anti-FGFR2 Recombinant Antibody (TAB-058WM) | ELISA, FC, Inhib | Rat IgG2a, κ |
| TAB-059WM | Anti-Human FGFR2 Recombinant Antibody (Atto-MuMab-01) | ELISA, WB, FC | |
| TAB-055WM-F(E) | Anti-Human FGFR2 Recombinant Antibody Fab Fragment (GP369/4B9) | ELISA, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-057WM | Human Anti-FGFR2 Recombinant Antibody (TAB-057WM) | ELISA, FC, Block | Human IgG1 |
| TAB-057WM-S(P) | Human Anti-FGFR2 Recombinant Antibody; scFv Fragment (TAB-057WM-S(P)) | ELISA, FC, Block | Human scFv |
| TAB-057WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-057WM-F(E)) | ELISA, FC, Block | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-060WM | Anti-Human FGFR2 Recombinant Antibody (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
| TAB-061WM | Human Anti-FGFR2 Recombinant Antibody (TAB-061WM) | Neut, WB, ELISA | Human IgG |
| TAB-060WM-S(P) | Anti-Human FGFR2 Recombinant Antibody scFv Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
| TAB-060WM-F(E) | Anti-Human FGFR2 Recombinant Antibody Fab Fragment (Atto-huMab-08) | ELISA, WB, FC | Human Antibody |
| TAB-061WM-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (TAB-061WM-F(E)) | Neut, WB, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-828CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL511) | WB, Neut | Mouse IgG1 |
| NEUT-829CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL512) | WB, FC, CyTOF®, Neut | Mouse IgG1 |
| NEUT-830CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL513) | FC, IHC, CyTOF®, Neut | Mouse IgG1 |
| NEUT-831CQ | Mouse Anti-FGFR2 Recombinant Antibody (NEUT-831CQ) | IHC, Neut, WB | Mouse IgG1 |
| NEUT-832CQ | Mouse Anti-FGFR2 Recombinant Antibody (clone CBL060) | Neut, WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1298 | Hi-Affi™ Rabbit Anti-FGFR2 Recombinant Antibody (clone DS1298AB) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-YC | Human Anti-FGFR2 Recombinant Antibody (clone Hu4B9-65) | FuncS | Humanized IgG1, κ |
| HPAB-0146-YC | Human Anti-FGFR2 Recombinant Antibody (HPAB-0146-YC) | ELISA, FC, Neut | Chimeric (rat/human) IgG |
| HPAB-0147-YC | Human Anti-FGFR2 Recombinant Antibody (HPAB-0147-YC) | ELISA, FC, Neut | Humanized IgG |
| MRO-0580-CN | Mouse Anti-FGFR2 Recombinant Antibody (clone 1-F1-E7) | WB, IF, FC | Mouse IgG1 |
| MRO-0581-CN | Mouse Anti-FGFR2 Recombinant Antibody (clone A5-E10-G7) | WB, IF, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0144-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone Hu4B9-65); Fab Fragment | FuncS | Humanized Fab |
| HPAB-0146-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-0146-YC-F(E)) | ELISA, FC, Neut | Human Fab |
| HPAB-0147-YC-F(E) | Human Anti-FGFR2 Recombinant Antibody; Fab Fragment (HPAB-0147-YC-F(E)) | ELISA, FC, Neut | Humanized Fab |
| HPAB-0674-WJ-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone M047-D08); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0361-YJ-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone CBF55YJ); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-027CN | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01) | ELISA, WB, FC | Human IgG1 |
| NS-027CN-F(E) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); Fab Fragment | ELISA, WB, FC | Human Fab |
| NS-027CN-S(P) | Human Anti-FGFR2 Recombinant Antibody (clone M048-D01); scFv Fragment | ELISA, WB, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-FY-S(P) | Mouse Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-0020-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-AP348-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP348-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
| HPAB-AP349-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP349-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
| HPAB-AP350-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP350-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
| HPAB-AP351-YC-S(P) | Rat Anti-FGFR2 Recombinant Antibody; scFv Fragment (HPAB-AP351-YC-S(P)) | ELISA, FC, Neut, ADCC, FuncS | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY132 | Human Anti-FGFR2 (clone 4B9) scFv-Fc Chimera | Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC624 | Recombinant Anti-FGFR2 Vesicular Antibody, EV Displayed (VS-0425-YC624) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2540 | Anti-FGFR2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2541 | Anti-Mouse FGFR2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2542 | Anti-Rat FGFR2 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, Cyt, PP, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
-2.png)
Application: Inhib, Cyt
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
Application: ELISA
Application: WB, IF, FuncS
-CB2006C17L-4.jpg)
Application: WB, ELISA
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, Cyt, PP, Inhib
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: Inhib, Cyt
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
