Recombinant Anti-human FGFR2 Intrabody [Tat] (CAT#: IAB-B026(T))

• Immunogen
• human fibroblast growth factor receptor 2

• Host Species
• mouse

• Type
• scFv-Tat

• Cell Penetrating Peptide
• TAT
  TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.

• Species Reactivity
• human

• Applications
• Products can be used for: Immunocytochemistry; Neutralization; Functional studies

• Purity
• >95% (SDS-PAGE)

• Storage
• Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.

• Alternative Names
• FGFR2; fibroblast growth factor receptor 2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; FGFR2-AHCYL1 fusion kinase protein;

• Gene ID
• 2263

• UniProt ID
• P21802

Select a product category from the dropdown menu below to view related products.