Human Anti-FGFR3 Recombinant Antibody (clone 2B.1.3) (CAT#: PABL-095)
Recombinant Human Antibody (2B.1.3) is capable of binding to FGFR3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-FGFR3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-FGFR3 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Specific Inquiry
Figure 1 shows the inhibitory effects of engineered 2B.1 antibodies for FGF7-stimulated MCF-7 cell proliferation. Error bars represent SEM.
Figure 2 shows the blocking of FGF-19 binding to human FGFR4.
Specifications
- Immunogen
- Human fibroblast growth factor receptor 3
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human FGFR3
- Species Reactivity
- Human
- Clone
- 2B.1.3
- Applications
- ELISA, WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Blocking. For details, refer to published data.
Target
- Alternative Names
- FGFR3; fibroblast growth factor receptor 3; ACH; CEK2; JTK4; CD333; HSFGFR3EX; FGFR-3; tyrosine kinase JTK4; hydroxyaryl-protein kinase; fibroblast growth factor receptor 3 variant 4
- Gene ID
- 2261
- UniProt ID
- P22607
Related Resources
Bladder Cancer
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 2B.1.3"
See other products for "FGFR3"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1249z | Mouse Anti-FGFR3 Recombinant Antibody (clone 3F6) | WB, ELISA, FC | Mouse IgG2a |
| MOB-0738CT | Recombinant Mouse anti-Human FGFR3 Monoclonal antibody (NN0380-7H22) | IHC-P, WB | |
| MRO-0582-CN | Rabbit Anti-FGFR3 Recombinant Antibody (clone JM81-10) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-0583-CN | Rabbit Anti-FGFR3 Recombinant Antibody (clone JM110-33) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-0150-WJ | Human Anti-FGFR3 Recombinant Antibody (HPAB-0150-WJ) | ELISA | Human IgG1 |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G028E | Anti-FGFR3 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G028G | Anti-FGFR3 immunotoxin (scFv)-Gel | Cytotoxicity assay, Function study | |
| AGTO-L016E | aFGF-PE immunotoxin | Cytotoxicity assay, Functional assay | |
| AGTO-L016G | aFGF-Gel immunotoxin | Cytotoxicity assay, Functional assay |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-095 | Human Anti-FGFR3 Recombinant Antibody (clone 2B.1.3); scFv Fragment | ELISA, WB, IF, FuncS | Human scFv |
| PFBW-162 | Human Anti-FGFR3 Recombinant Antibody (clone R3); Fab Fragment | Neut, ELISA, FC | Human Fab |
| PSBL-471 | Human Anti-FGFR3 Recombinant Antibody (clone R3Mab); scFv Fragment | ELISA | Human scFv |
| HPAB-0157-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0157-YC-S(P)) | ELISA, IP, WB | Human scFv |
| HPAB-0150-WJ-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0150-WJ-S(P)) | ELISA | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-062WM | Mouse Anti-FGFR3 Recombinant Antibody (TAB-062WM) | ELISA, FC, Neut, WB | Mouse IgG |
| TAB-063WM | Mouse Anti-FGFR3 Recombinant Antibody (TAB-063WM) | ELISA, FC, Neut, WB | Mouse IgG |
| TAB-064WM | Anti-Human FGFR3 Recombinant Antibody (15D8) | Neut, ELISA | |
| TAB-062WM-S(P) | Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-062WM-S(P)) | ELISA, FC, Neut, WB | Mouse scFv |
| TAB-063WM-S(P) | Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-063WM-S(P)) | ELISA, FC, Neut, WB | Mouse scFv |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-834CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL546) | Neut | Mouse IgG1 |
| NEUT-835CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL547) | WB, Neut | Mouse IgG1 |
| NEUT-836CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone 6G11) | WB, Neut | Mouse IgG1 |
| NEUT-837CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL061) | WB, IHC, Neut | Mouse IgG1 |
| NEUT-838CQ | Rat Anti-Fgfr3 Recombinant Antibody (clone CBL548) | Neut | Rat IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1299 | Hi-Affi™ Rabbit Anti-FGFR3 Recombinant Antibody (clone DS1299AB) | WB, IHC, ICC, FC | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0157-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0157-YC-F(E)) | ELISA, IP, WB | Human Fab |
| HPAB-0158-YC-F(E) | Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0158-YC-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0159-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-0160-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody (clone PRO-001); Fab Fragment | FC, FuncS | Human Fab |
| HPAB-0161-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody (clone PRO-055); Fab Fragment | FC, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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