Recombinant Anti-human FOLR1 Intrabody [(D-Arg)₉] (CAT#: IAB-B029(A))

• Immunogen
• human folate receptor 1 (adult)

• Host Species
• mouse

• Type
• scFv-(D-Arg)₉

• Cell Penetrating Peptide
• (D-Arg)₉
  It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.

• Species Reactivity
• human

• Applications
• Can be useful in applications such as: Protein fragment complementation; Neutralization; Functional studies

• Purity
• >98% by SDS-PAGE and HPLC analysis

• Storage
• 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

• Alternative Names
• FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18

• Gene ID
• 2348

• UniProt ID
• A0A024R5H1

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