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  • Recombinant Anti-human FRMD4A Intrabody [+36 GFP]

Recombinant Anti-human FRMD4A Intrabody [+36 GFP] (CAT#: IAB-B059(G))

Recombinant anti-FRMD4A intrabody in fusion with +36GFP works within cells to direct against human FRMD4A, expressed in CHO cells. The intrabody can be used in therapeutic methods for treating proliferative disorders, including squamous cell carcinoma (SCC).


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Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/79254_B_7_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Peripheral nerve/ganglion Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/79254_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/79254_A_9_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/79254_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/79254_A_4_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/38449/79254_A_8_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (hTEC/SVTERT24-B, HUVEC TERT2, TIME, WM-115)
Figure 8 RNA cell line category: Cell line enhanced (hTEC/SVTERT24-B, HUVEC TERT2, TIME, WM-115)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000151474-FRMD4A

Specifications

  • Immunogen
  • human FERM domain containing 4A
  • Host Species
  • human
  • Type
  • scFv-(+36GFP)
  • Cell Penetrating Peptide
  • +36 GFP
    GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
  • Species Reactivity
  • human
  • Applications
  • Antibody assay: Enzyme-linked Immunosorbent Assay; Immunofluorescence; Neutralization; Functional studies

Product Property

  • Purity
  • >90% assessed by SDS-PAGE
  • Storage
  • ≤1 year at -20°C.

Target

  • Alternative Names
  • FRMD4A; FERM domain containing 4A; FRMD4; bA295P9.4; FERM domain-containing protein 4A; FERM domain containing 4

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "FRMD4A"

Intrabody

CAT Product Name Application Type
IAB-B059(A) Recombinant Anti-human FRMD4A Intrabody [(D-Arg)9] CO-IP, FuncS scFv-(D-Arg)9
IAB-B059(T) Recombinant Anti-human FRMD4A Intrabody [Tat] FC, IF, FuncS scFv-Tat

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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