Hi-Affi™ Rabbit Anti-FURIN Recombinant Antibody (clone DS1364AB)
CAT#: MOR-1364
Recombinant Rabbit anti-FURIN monoclonal antibody for ICC/IF, IHC-P, WB, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9499/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Nucleoplasm & Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9499/992_E8_1_blue_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67869/168556_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67869/168556_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67869/168556_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67869/168556_A_5_6.jpg
RNA Expression
Figure 7 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140564-FURIN
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Specifications
- Immunogen
- Recombinant fragment within Human Furin aa 200-350.
- Host Species
- Rabbit
- Derivation
- Phage display library
- Type
- Rabbit IgG
- Specificity
- Human FURIN
- Species Reactivity
- Mouse, Rat, Human
- Clone
- DS1364AB
- Applications
- ICC, IF, IHC-P, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Furin, Paired Basic Amino Acid Cleaving Enzyme; Furin (Paired Basic Amino Acid Cleaving Enzyme); Paired Basic Amino Acid Residue-Cleaving Enzyme; EC 3.4.21.75; PCSK3; PACE; FUR; Paired Basic Amino Acid Cleaving Enzyme (Furin, Membrane Associated Receptor Protein); Proprotein Convertase Subtilisin/Kexin Type 3; Furin, Membrane Associated Receptor Protein; Dibasic Processing Enzyme; Dibasic-Processing Enzyme; FES Upstream Region; EC 3.4.21; SPC1
- Gene ID
- 5045
- UniProt ID
- P09958
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "FURIN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-593-sdAb | Recombinant Anti-human FURIN VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| PABC-557 | Recombinant Arabian camel Anti-FURIN Single Domain Antibody (PABC-557) | ELISA, Inhib, IP | Arabian camel VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2412MZ | Recombinant Mouse Anti-Human FURIN Antibody (clone NN0309-5H42) | IHC-P, WB | Mouse antibody |
| MRO-0613-CN | Rabbit Anti-FURIN Recombinant Antibody (clone JB35-53) | WB, IHC, IF | Rabbit IgG |
| ZG-0005U | Rabbit Anti-FURIN Recombinant Antibody (clone 1C3) | ELISA, WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY873 | Anti-FURIN Immunohistochemistry Kit | IHC | |
| VS-0525-XY2669 | Anti-Human FURIN Immunohistochemistry Kit | IHC |
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